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Background and purpose: Cancer is the one common cause of death in developed and the developing countries. Still gastrointestinal cancers is a major cause of Deaths from cancerin the north of the IRAN, this part is a place that located on the Esophageal Cancer belt. As well as is one of esophageal cancer focuses in the world. At the north east of IRAN such as TORKAMAN SAHRA that reaches a maximum value. Studying the spatial variation of esophageal and gastric cancer in different parts of the Golestan province and its relationship with soil conditions of that area. Esophageal Cancer is appear often in an advanced stage so that in half of the patients is advanced with localized disease at diagnosis. Materials and methods: In this study, cancer of the esophagus and stomach, and the sum of them was evaluated using spatial statistics. It was compared with different models of spatial statistics.Finally, Universal kriging map of the esophagus and stomach cancer was drawn. Results: ASR ratio of esophageal cancer is: min 58/5 and max 27/680Valu of the optimal model for exponent changing of esophageal cancer, exponential model and gastric cancer is Gaussian model. Regions with the largest changes in loess deposits are located at North-East of Province that the maximum amount of esophageal and gastric cancer are observed in is part. Conclusion: Maps derived from this study shown, esophageal cancer in Golestan province is more acute than gastric cancer. Map of incidence of cancer from west to east is more dens. KALALEH city has most of loess sediments, also amount of esophageal cancer is the maximum

Keywords: Esophageal Cancer, Golestan, Loess Soil, Geo Statistic

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