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Background and purpose: Today, most organizations have recognized the value of their invisible assets and seek multiple methods to use them efficiently. One of these invisible assets is knowledge and knowledge management is a process of creating value from knowledge implementation. Execution of knowledge management requires paying attention to important factors such as organizational culture and information technology. The importance of these factors varies in different organizations according to organizational goals, organizational activities, the environment in which the organization is located, the amount of information and knowledge of the staff and facilities. This study was conducted to investigate the key factors in the establishment of knowledge management in administrative offices of Mazandaran University of Medical Sciences Materials and methods: This descriptive survey was conducted among the managers and the staff working in administrative offices of Mazandaran University of Medical Sciences. Morgan table was used and 200 people were selected of whom 189 (97 female and 88 male) completed a questionnaire. The questionnaire included 55 questions regarding information technology, organizational culture and knowledge management, and some questions on demographic features. Data analysis was done using IBM SPSS 20. Results: The result of this study showed significant differences between the knowledge of female and male subjects and the female case’s knowledge was lower than male cases (P <0.039). On the other hand there were significant association between support executives, sense of organization, collaboration, and management of information technology and knowledge management, but no significant correlation was found between trust and process information Conclusion: Due to the importance of knowledge management for organizations and interconnected nature of organizational culture and IT, staff should receive supports to maximally benefit from their experience and knowledge, thereby the most advanced information systems are created.

Keywords: Knowledge management, organizational culture, management support, confidence, sense of organization

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