Volume 10, Issue 26 (Mar 2000)                   J Mazandaran Univ Med Sci 2000, 10(26): 7-12 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Saffar M, Ânamee M. Determination of Immune Persistancy measles vaccine six years after vaccination. Does the booster dose required? . J Mazandaran Univ Med Sci 2000; 10 (26) :7-12
URL: http://jmums.mazums.ac.ir/article-1-283-en.html
Abstract:   (19421 Views)
Background and purpose: Due to the minor outbreak of measles in the vaccinated individuals, and also, its shifting incidence from infancy to the school age there is concern on the hypotesis decline immune status to measles as the time passes. This study was designed to determine this hypothesis.
Materials and methods: The study was a cohort one. Two groups comprised of 225 children of 16-18 months and 7- 7 ½ years were selected. There was a delay of 4-6 weeks in booster dose of the first group (test). Ând 6- 6 ½ years in the second group(control). Their anti measles ÏgG was measured by ËLÏSÂ method.
Results: Ïn the test group G out of 225 persons(2.6%) and in control group 13 out of 225 persons (5.7%) were not immune to measles which was not statistically significant.
Çonclusion: The evidence to prove the decline of immune status of measles vaccine in long term was invaluable. Hence the repeatation of measles vaccine at the age of school entrance is not recommended. But another similar study at higher age (10-20 years after vaccination) to determine the stability of immune status to measles is proposed.
Full-Text [PDF 134 kb]   (2488 Downloads)    
Type of Study: Research(Original) |

Add your comments about this article : Your username or Email:
CAPTCHA

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb