Abstract: (6800 Views)
Background and purpose: Probiotics and prebiotics are new concepts which have been
demonstrated to positively modulate the intestinal micro flora and could promote host health. The aim of
this study was to evaluate the effects of prebiotics on production of antimicrobial properties of
Lactobacillus acidophilus ATCC4356 ، Lactobacillus plantarum ATCC 8014 Lactobacillus fermentum
ATCC 9338 Lactobacillus rhamnosus ATCC 7469, and Lactobacillus casei ATCC 39392 against growth
or activity of Proteus vulgaris.
Materials and methods: Antimicrobial activity of bacterial culture supernatant was tested
using Agar Well Diffusion (AWD) method in two medium compositions: basic MRS broth and MRS
broth with Inulin, Trehalose, Raffinose, Lactulose, and Riboflavin as prebiotic.
Results: Results showed that prebiotics were able to increase antimicrobial activity. Zone of
inhibition in presence of prebiotic for Lactobacillus spp. increased up to 29/67 mm.
Conclusion: According to the results, prebiotics could increase antimicrobial activity of
Lactobacillus spp. and this activity of Lactobacillus was specifically strain dependent and related to kind
of prebiotics. Therefore, probiotic products efficiency could be increased in presence of specific prebiotic
properties.