Volume 24, Issue 121 (2-2015)                   J Mazandaran Univ Med Sci 2015, 24(121): 31-38 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Mousavinasab S N, Yazdani Cherati J, Karami H, Khaksar S. Risk Factors Influencing the Survival of Pediatric Acute Leukemia Using Competing Risk Model. J Mazandaran Univ Med Sci 2015; 24 (121) :31-38
URL: http://jmums.mazums.ac.ir/article-1-5117-en.html
Risk Factors Influencing the Survival of Pediatric Acute Leukemia Using Competing Risk Model
Seyed Nooredin Mousavinasab , Jamshid Yazdani Cherati , Hossein Karami , Shahrbanoo Khaksar
Abstract:   (7035 Views)
Background and purpose: Acute leukemia is a malignancy with a rapidly progressive course of the lymphoid or myeloid cells. A prognostic factor for its survival and treatment is of particular importance in medical research. Therefore, this study aimed at applying competing risk model to compare clinical and pathologic factors in pediatric acute leukemia. Materials and methods: A historical cohort analysis was performed on survival data of 97 children with acute leukemia collected from Pediatric Oncology Department in Booali Sina Hospital in Sari from 2006 to 2014. We recorded data including age at diagnosis, type of leukemia, sex, white blood cell count, and platelet count. Statistical analysis using competing risk model, Cox regression model and STATS software were performed. Results: The median follow-up period was 14.83 mounts during which 27 patients (27.83%) (17 ALL cases and 10 AML cases) passed away. In competing risk model significant relationship was found between type of leukemia, hemoglobin count and white blood cell count with survival time. Conclusion: In order to identify the prognostic risk factors on the survival of patients with acute leukemia, in presence of competing risks, using the competing risk regression model was found more efficient compared to cox regression model.
Keywords: Competing risk, survival time, acute leukemia
Full-Text [PDF 199 kb]   (2866 Downloads)    
Type of Study: Research(Original) | Subject: Biostatistics
Add your comments about this article : Your username or Email:
CAPTCHA
Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb