Volume 20, Number 76 (May 2010)                   J Mazandaran Univ Med Sci 2010, 20(76): 24-31 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nasiri E, Soliamani A, Mohammadpour R, Donyavi R, Jafari H. Comparison between the effectcs of remifentanil and fentanyl on blood pressure and cardiac dysrythmia during tracheal intubation in CABG. J Mazandaran Univ Med Sci. 2010; 20 (76) :24-31
URL: http://jmums.mazums.ac.ir/article-1-610-en.html

Abstract:   (8991 Views)
Background and purpose: Ït has been found that the use of different drugs for laryngoscopy preparation and tracheal intubation results in controversy. The aim of this study is to compare the haemodynamic effects of remifentanil with fentanyl for tracheal intubation in patients undergoing coronary artery bypass grafting (ÇÂBG).
Materials and methods: This is a randomized and double-blind study. We recruited 64 patients undergoing coronary artery bypass surgery. Subjects received in 3 separate groups: remifentanil, 5 microgram/kg, Fentanyl, 8 microgram/kg, and routine medication respectively. Systolic and diastolic blood pressure, heart rate and mean arterial pressure were measured during, before and after tracheal intubation and immediately, 1, 3, 5, 10, minutes after intubation. Patients were monitored for haemodynamic changes using electrocardiography.
Results: Sixty four patients were enrolled in the study. Twenty four patients age at 66 ± 5.7 (60-84) years, received remifentanil, 23 patients with mean age of 65.7 ± 6 (60-80) years made up the routin group, and 17 patients with mean age of 65 ± 4.8 (61-76) years received fentanyl. Blood pressure and heart rate decreased after induction of anaesthesia in all groups. SBP and DBP significantly decreased in remifentanil group in comparison with other groups (p= 0.01, 0.03). Ït was pssoble to control hemodynamic response to tracheal intubation in all groups, although it was better in remifentanil group than other groups.
Çonclusion: Âlthough the incidence of hypotension was higher, 0.5 microgram/kg of Remifentanil 8 microgram/kg of fentanyl and routine method (sufentanil) were all effective to attenuate patients’ blood pressure in response to tracheal intubation up to 3 minutes after intubation.
Full-Text [PDF 595 kb]   (1149 Downloads)    
Type of Study: Research(Original) |

Add your comments about this article : Your username or email:
Write the security code in the box

Send email to the article author


© 2015 All Rights Reserved | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb