TY - JOUR T1 - The Comparison of Priming with Pancrunium and Atracurium in the Speed of Providing Adequate Neuromuscular Blockade for Tracheal Intubating TT - بررسی مقایسه ای استفاده از دوز اولیه (Priming Dose ) پانکرونیوم و آتراکوریوم از نظر زمان ایجاد شلی کافی برای لوله گزاری تراشه JF - J-Mazand-Univ-Med-Sci JO - J-Mazand-Univ-Med-Sci VL - 17 IS - 58 UR - http://jmums.mazums.ac.ir/article-1-211-en.html Y1 - 2007 SP - 37 EP - 42 KW - Pancrunium KW - Atracurium KW - Priming KW - Tracheal intubation N2 - Background and purpose: Neuromuscular relaxants are one group of the important drugs in providing good condition for tracheal intubation and operation. Rapid intubation is needed in most situations. Also, most of non- depolarizing relaxants almost have long onset time. We compared the priming with pancrunium and atracurium in providing good and rapid relaxation for tracheal intubation. Materials and Methods: In this prospective study, 65 patients with ASA class I, II were randomized into two groups. Group A received pancrunium and group B received atracurium. Primimg dose was injected as 20% of total dose of relaxant. Twitching response was measured with peripheral nerve stimulator. Intubation was done when % 80 of the twitching response disappeared. The time of total disappearance of twitching response was also recorded. Results: The mean time for the injection of the first dose of relaxant until the time of intubation was 94.47 seconds in group A and 142.9 seconds in group B, which were significantly different (P M3 ER -