%0 Journal Article %A Kaviani, M %A Nourshahi, M %A Shokoohi, F %T The effects of acute L-carnitine administration on ventilatory breakpoint and exercise performanceduring incremental exercise %J Journal of Mazandaran University of Medical Sciences %V 19 %N 73 %U http://jmums.mazums.ac.ir/article-1-587-en.html %R %D 2009 %K Exercise; carnitine; anaerobic threshod, %X Background and purpose:Many athletes adopt nutritional manipulations to improve their performance. Among the substances generally consumed is carnitine (L-trimethyl-3-hydroxy-ammoniobutanoate) which has been used by athletes as an ergogenic aid, due to its role in the transport of long-chain fatty acids across mitochondrial membranes. Nutritional supplements containing carbohydrates, proteins, vitamins, and minerals have been widely used in various sporting fields to provide a boost to the recommended daily allowance. The aim of this study is to investigate the effects of acute L-carnitine administration on ventilatory breakpoint, an exercise performance during incremental exercise. Materials and methods: This study was double-blind, randomized and crossover in design. The subjects were 12 randomly selected active male physical education students, 21.75±0.64 years old, with a mean body mass index (BMI) of 23.7±0.94kg/m2, divided into 2 groups. They received orally either 2g of L-carnitine dissolved in 200 ml of water, plus 6 drops of lemon juice or a placebo (6 ml lemon juice dissolved in 200 ml of water) 90 minutes before they began to exercise on a treadmill. They performed a modified protocol of Conconi test to exhaustion. One-way analysis of variance with repeated measurements was used for data analysis. Results:The results showed that exercise performance improved in LC group (2980±155 meter) compared with placebo group (2331±51 meter). Furthermore, no significant difference was found in ventilatory breakpoint between the two groups. Conclusion:This finding indicates that administration of L- Carnitine, 90 minutes prior to exercise may improve performance despite the ventilatory breakpoint as one of the anaerobicsystem indices that had no effect. %> http://jmums.mazums.ac.ir/article-1-587-en.pdf %P 42-50 %& 42 %! %9 Research(Original) %L A-10-1-587 %+ %G eng %@ 1735-9260 %[ 2009