fa تاثیر حاد مواد استنشاقی بر تغییرات امواج الکتروانسفالوگرافی کمی روانپزشکی psychiatry پژوهشي-کامل Research(Original) <strong>&nbsp;</strong><span style="font-size:12pt"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="FA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">سابقه</span></span></span></span><span lang="AR-SA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt"> و هدف:</span></span></span></span> <span b="" style="font-family:" zar="">مواد استنشاقی، هیدروکربن‌هایی هستند که در دمای اتاق به حالت گاز تبدیل شده و از طریق بینی و دهان وارد ریه و سپس </span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">مغز می</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">شوند. با وجود اثرات نورولوژیکی و روانپزشکی ناشی از مصرف مواد استنشاقی، مطالعات اندکی در مورد اثرات حاد مواد استنشاقی بر روی مغز صورت گرفته است. لذا مطالعه حاضر به تاثیر حاد مواد استنشاقی بر تغییرات امواج الکتروانسفالوگرافی کمی پرداخته است.<span style="color:#0e101a"></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">مواد و روش</span></span></span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.1pt">‌</span></span></span></span><span lang="AR-SA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">ها:</span></span></span></span> <span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">این مطالعه مشاهده‌ای در بیمارستان زارع ساری در واحد ابزاری تشخیصی در سال 1399 انجام شد. 20 نفر که از لاک پاک کن حاوی استون به منظورهای آرایشی استفاده می</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">کردند، در مطالعه شرکت کردند. سیگنال</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">های مغز قبل و حین و 3 دقیقه اول و 3 دقیقه دوم بعد از استفاده از این لاک پاک</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">کن</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">ها از طریق الکتروانسفالوگرافی کمی (</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">QEEG</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">) در حالت چشم باز افراد ثبت شد. توان نسبی امواج در لوب‌های پس سری، پیشانی، آهیانه</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">ای و خط میانه با نرم</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">افزار نوروگاید محاسبه گردید. آنالیز داده</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">ها توسط نرم</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">افزار </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">STAT</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">A</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">-15</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""> انجام شد.</span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="letter-spacing:-.2pt">یافته</span></span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.2pt">‌</span></span></span><span lang="AR-SA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="letter-spacing:-.2pt">ها:</span></span></span> <span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">قدرت نسبی امواج بتا، دلتا در حین، سه دقیقه اول و دوم از مصرف</span></span> <span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">لاک پاک کن استونی در نقاط </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">C3</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">C4</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">Cz</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">F3</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">،</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"> F4 </span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">Fz</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">O1</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">O2</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">P3</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">، </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">P4</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""> و </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">Pz</span></span><span style="line-height:92%"><span b="" style="font-family:" zar=""> (0/01</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%">P<</span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">) به</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">طور معنی</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar="">داری<span style="color:black"> افزایش یافت(0/01</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="color:black">P<</span></span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""><span style="color:black">). در حالی که توان نسبی باند آلفا کاهش معنی</span></span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""><span style="color:black">داری در نقاط مذکور داشت و توان نسبی باند تتا تغییری نداشت.</span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:92%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:92%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">استنتاج:</span></span></span></span> <span lang="AR-SA" style="line-height:92%"><span b="" style="font-family:" zar="">در این مطالعه </span></span><span lang="FA" style="line-height:92%"><span b="" style="font-family:" zar=""><span style="color:black">مواجهه فوری با ماده استنشاقی استون موجب افزایش قدرت نسبی باند فرکانسی دلتا و بتا و کاهش باند فرکانسی آلفا در پیشانی، آهیانه‌ای، پس سری و خط میانه در هر دو نیمکره می‌شود.</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:92%"><span style="color:black"><span style="letter-spacing:-.2pt"></span></span></span></span></span></span></span></span></span></span></span><br> &nbsp; <strong>&nbsp;</strong><span style="font-size:12pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:"><span style="letter-spacing:-.2pt">Background and purpose:</span></span></span></span></b> <span style="font-size:10.0pt"><span style="line-height:150%">Inhaling substances are hydrocarbons that are converted to gas at room temperature and enter the lungs through the nose and mouth and then our brain. Neurological and psychiatric effects are reported following inhalation, however, there are few studies about acute effect of inhalant on brain electroencephalogram (EEG).</span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:150%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Materials and methods:</span></span></span></b><b> </b><span lang="EN" style="font-size:10.0pt"><span style="line-height:150%">This observational study was performed in </span></span><span style="font-size:10.0pt"><span style="line-height:150%">Quantitative Electroencephalography unit in</span></span><span lang="EN" style="font-size:10.0pt"><span style="line-height:150%"> Sari Zare Hospital, 2020. </span></span><span style="font-size:10.0pt"><span style="line-height:150%">Twenty people who used nail polish containing aceton for cosmetic usages participated in this study. Brain signals were recorded before, during, at first and second three minutes after termination of using nail polish containing acetone, were recorded by mitsar 201 amplifier in eyes-open condition. The relative power of the band frequency waves in the occipital, frontal, parietal and midline lobes were calculated using Neurogide software. Data analysis was performed in STATA-15.</span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Results:</span></span></span></b><b> </b><span style="font-size:10.0pt"><span style="line-height:150%">During acetone nail polish use and at first and second 3 minutes after that relative power <span style="letter-spacing:-.2pt">in delta </span></span></span><span style="font-size:10.0pt"><span style="line-height:150%"><span style="letter-spacing:-.2pt">and beta</span></span></span><span style="font-size:10.0pt"><span style="line-height:150%"><span style="letter-spacing:-.2pt"> band waves significantly increased in C₃, C₄, Cz, F₃, F₄, Fz, O₁, O₂, P₃, P₄, and Pz (P<0.01)</span></span></span><span style="font-size:10.0pt"><span style="line-height:150%"> while relative power of alpha frequency band significantly decreased (P<0.01). Theta frequency band showed no changes.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span style="vertical-align:top"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Conclusion:</span></span></span></b> <span style="font-size:10.0pt"><span style="line-height:150%">In this study, acute exposure to acetone increased relative power of delta </span></span><span style="font-size:10.0pt"><span style="line-height:150%">and beta</span></span><span style="font-size:10.0pt"><span style="line-height:150%"> waves and reduced relative power of alpha waves, in frontal, parietal, occipital, and midline regions in both hemispheres. </span></span><i><span style="font-size:10.0pt"><span style="line-height:150%"></span></span></i></span></span></span></span><br> <span dir="RTL"></span> مواد استنشاقی, استنشاق, حاد, امواج مغزی, استون,الکتروانسفالوگرافی, قدرت نسبی inhalant, inhalation, acute, brain waves, acetone, electroencephalogram, relative power 59 70 http://jmums.mazums.ac.ir/browse.php?a_code=A-11-14146-1&slc_lang=fa&sid=1 Javad Setareh جواد ستاره javad_setareh@yahoo.com 1003194753284600145790 1003194753284600145790 Yes Assistant Professor, Department of Psychiatry, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran استادیار، گروه روانپزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران Eileen TeymooriAlanjareghi آیلین تیموری النجارقی eileen.t.1987@gmail.com 1003194753284600145791 1003194753284600145791 No Resident in Psychiatry, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran دستیار روانپزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران AliAsghar NadiGhara علی اصغر نادی قرا statistic.nadi@gmail.com 1003194753284600145792 1003194753284600145792 No PhD in Statistics, Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran دکترای آمار، مرکز تحقیقات علوم بهداشتی، پژوهشکده اعتیاد، دانشگاه علوم پزشکی مازندران، ساری، ایران Marzieh Rafiee مرضیه رفیعی eileen.t.1987@gmail.com 1003194753284600145793 1003194753284600145793 No BSc in Nursing, Laboratory of the Sleep Disorder, Mazandaran University of Medical Sciences, Sari, Iran کارشناسی پرستاری،کلینیک خواب، دانشگاه علوم پزشکی مازندران، ساری، ایران