fa تاثیر غرغره آبلیموعسل بر سرفه، گلودرد و خشونت صدای بعد از اکستوباسیون لوله تراشه: یک مطالعه کارآزمایی بالینی گیاهان دارویی Medicinal Plant پژوهشي-کامل Research(Original) <strong>&nbsp;</strong><span style="font-size:12pt"><span style="line-height:89%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="FA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">سابقه</span></span></span></span><span lang="AR-SA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt"> و هدف:</span></span></span></span> <span b="" style="font-family:" zar="">سرفه، خشونت صدا و گلودرد از عوارض اینتوباسیون است. هدف از این مطالعه بررسی تاثیر غرغره محلول آبلیموعسل بر سرفه، گلودرد و خشونت صدای بعد از اکستوباسیون لوله تراشه در بیماران تحت عمل جراحی بود.</span><span b="" style="font-family:" zar=""><span style="color:#0e101a"></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:89%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">مواد و روش</span></span></span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.1pt">‌</span></span></span></span><span lang="AR-SA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">ها:</span></span></span></span> <span b="" style="font-family:" zar="">در این مطالعه کارآزمایی بالینی در بیمارستان22 بهمن</span> <span b="" style="font-family:" zar="">نیشابور</span> <span b="" style="font-family:" zar="">در سال 1398 </span><span b="" style="font-family:" zar="">، تعداد 110 بیمار تحت <span style="letter-spacing:-.1pt">عمل جراحی با روش نمونه</span></span><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">‌</span></span><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">گیری در دسترس به دو گروه کنترل و آزمون تخصیص تصادفی شدند. در گروه آزمون، 6 ساعت</span></span><span b="" style="font-family:" zar=""> بعد از عمل، 30 سی سی محلول آبلیمو عسل، طی سه مرحله و به فاصله هر دو ساعت، توسط بیمار غرغره و سپس بلع شد. گروه کنترل، تنها مداخلات روتین بخش را دریافت کرد. شدت گلودرد، سرفه و خشونت صدای بیماران قبل از مداخله، </span><span b="" style="font-family:" zar="">12</span><span b="" style="font-family:" zar=""> و 24 ساعت بعد از</span><span b="" style="font-family:" zar=""> اکستوباسیون در دو گروه </span><span b="" style="font-family:" zar="">مقایسه شد. داده</span><span b="" style="font-family:" zar="">‌</span><span b="" style="font-family:" zar="">ها با آزمون کای اسکوئر، تی مستقل و آنالیز واریانس با اندازه تکراری تحلیل شد.</span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="color:black"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:89%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">یافته</span></span></span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.2pt">‌</span></span></span></span><span lang="AR-SA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">ها:</span></span></span></span> <span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">یافته</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">ها نشان داد که 12 ساعت بعد از اکستوباسیون اختلاف معناداری بین دو گروه از نظر سرفه و شدت گلودرد وجود نداشت، اما امتیاز خشونت صدا در گروه آزمون کم</span></span><span b="" style="font-family:" zar="">‌</span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">تر (</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:89%">0/05</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">=P) بود. 24 ساعت بعد از اکستوباسیون میزان <span style="letter-spacing:-.1pt">سرفه (0/001=</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:89%"><span style="letter-spacing:-.1pt">P</span></span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">)، خشونت صدا (0/006=</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:89%"><span style="letter-spacing:-.1pt">P</span></span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">) و شدت گلودرد (0/023=</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:89%"><span style="letter-spacing:-.1pt">P</span></span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">) در گروه آزمون به</span></span></span><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">‌</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">طور معنی</span></span></span><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">‌</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">داری کم</span></span></span><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">‌</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">تر از گروه</span></span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""> کنترل بود. گذشت زمان نیز در طی سه مرحله مطالعه، بر هر سه متغیر تاثیر معنی</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">‌</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">داری داشت (0/001</span></span><span lang="FA" style="font-size:10.0pt"><span style="line-height:89%"><span b="" style="font-family:" zar="">></span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:89%">P</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar="">).</span></span><span lang="FA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="color:black"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:89%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:89%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">استنتاج:</span></span></span></span> <span b="" style="font-family:" zar="">با توجه به اثرات مثبت غرغره محلول آبلیموعسل در کاهش عوارض لوله تراشه و عدم گزارش عوارض جانبی، توصیه می‌شود بعد از اکستوباسیون این روش مورد استفاده قرار گیرد.</span><span lang="AR-SA" style="line-height:89%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.2pt"></span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:89%"><span style="tab-stops:102.0pt 135.0pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="font-size:6.0pt"><span style="line-height:89%"><span b="" style="font-family:" zar=""><span style="color:black"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:89%"><span style="tab-stops:284.5pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="FA" style="font-size:10.0pt"><span style="line-height:89%"><span b="" style="font-family:" zar="">شماره ثبت کارآزمایی بالینی : 4</span></span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:89%">N</span></span><span lang="FA" style="font-size:10.0pt"><span style="line-height:89%"><span b="" style="font-family:" zar="">20150511022218</span></span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:89%">IRCT</span></span><span lang="FA" style="font-size:10.0pt"><span style="line-height:89%"><span style="font-family:"B Zar""></span></span></span></span></span></span></span></span></span><br> <span dir="LTR"></span> &nbsp;<span style="font-size:12pt"><span style="line-height:135%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:135%"><span arial="" style="font-family:"><span style="letter-spacing:-.2pt">Background and purpose:</span></span></span></span></b> <span style="font-size:10.0pt"><span style="line-height:135%">Cough, hoarseness, and sore throat are complications of intubation. The aim of this study was to evaluate the effect of gargling with honey and lemon water on cough, sore throat, and hoarseness after extubation of endotracheal tube following surgery.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:135%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:135%"><span arial="" style="font-family:">Materials and methods:</span></span></span></b><b> </b><span style="font-size:10.0pt"><span style="line-height:135%">A clinical trial was carried out in 110 patients undergoing surgery in </span></span><span style="font-size:10.0pt"><span style="line-height:135%">Neyshabur</span></span><span style="font-size:10.0pt"><span style="line-height:135%"> 22 Bahman Hospital, Iran 2020. They were selected using convenience sampling and randomly allocated to experimental or control group. In experimental group, 6 hours after surgery, 30 cc of honey lemon water was gargled, three times, every two hours and then swallowed. The control group received routine care. Postoperative sore throat, cough, and hoarseness were assessed before the intervention, and 12 and 24 hours after extubation of endotracheal tube.</span></span> <span style="font-size:10.0pt"><span style="line-height:135%">Data were analyzed by independent t-test and repeated measures analysis of variance. </span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:135%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:135%"><span arial="" style="font-family:">Results:</span></span></span></b><b> </b><span style="font-size:10.0pt"><span style="line-height:135%">Findings showed no significant difference between the two groups in cough and sore throat 12 hours after extubation, but the score for hoarseness was lower in experimental group (P= 0.05).</span></span> <span style="font-size:10.0pt"><span style="line-height:135%">Twenty-four hours after extubation, cough (P= 0.001), hoarseness (P= 0.006), and sore throat (P= 0.023) were significantly lower in experimental group. The passage of time was found to significantly affect all three variables (P<0.001).</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:135%"><span style="vertical-align:top"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:135%"><span arial="" style="font-family:">Conclusion:</span></span></span></b> <span style="font-size:10.0pt"><span style="line-height:135%">Considering the positive effects of gargling with honey and lemon water in reducing the complications of endotracheal tube and no side effects, it is recommended to be used after extubation.</span></span><i><span style="font-size:10.0pt"><span style="line-height:135%"></span></span></i></span></span></span></span><br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:7.0pt"><span style="letter-spacing:-.1pt"></span></span></b></span></span><br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><span style="font-size:8.0pt"><span style="letter-spacing:-.1pt">(Clinical Trials Registry Number: </span></span><span style="font-size:8.0pt"><span style="letter-spacing:-.1pt">IRCT20150511022218N4</span></span><span style="font-size:8.0pt"><span style="letter-spacing:-.1pt">)</span></span><b><i><span style="font-size:8.0pt"><span style="letter-spacing:-.1pt"></span></span></i></b></span></span><br> &nbsp; سرفه, خارج سازی لوله تراشه, خشونت صدا, گلو درد, عسل Cough, endotracheal extubation, hoarseness, sore throat, honey 27 38 http://jmums.mazums.ac.ir/browse.php?a_code=A-10-14773-1&slc_lang=fa&sid=1 Nahid Rajai ناهید رجایی n.rajai22@yahoo.com 1003194753284600145153 1003194753284600145153 No Instructor, Department of Maternal and Neonatal Health, Army School of Nursing, Aja University of Medical Sciences, Tehran, Iran مربی، گروه آموزشی بهداشت مادران و نوزادان، دانشکده پرستاری ارتش، دانشگاه علوم پزشکی آجا، تهران، ایران Mohammadreza Aryaeefar محمدرضا آریایی فر m.aryaee2012@gmail.com 1003194753284600145154 1003194753284600145154 Yes Instructor, Department of Operating Room, Neyshabur University of Medical Sciences, Neyshabur, Iran مربی، گروه آموزشی اتاق عمل، دانشگاه علوم پزشکی نیشابور، نیشابور، ایران Amir Hosein Pishgooie امیر حسین پیشگویی apishgooie@yahoo.com 1003194753284600145155 1003194753284600145155 No Associate Professor, Department of Intensive Care Nursing, Army School of Nursing, Aja University of Medical Sciences, Tehran, Iran دانشیار، گروه آموزشی پرستاری مراقبت ویژه، دانشکده پرستاری ارتش، دانشگاه علوم پزشکی آجا، تهران، ایران Vahid Moeini وحید معینی v.moini@yahoo.com 1003194753284600145156 1003194753284600145156 No Instructor, Department of Operating Room, Neyshabur University of Medical Sciences, Neyshabur, Iran. مربی، گروه آموزشی اتاق عمل، دانشگاه علوم پزشکی نیشابور، نیشابور، ایران Ali Movahedi علی موحدی 1003194753284600145157 1003194753284600145157 No Instructor, Department of Anesthesia, Neyshabur University of Medical Sciences, Neyshabur, Iran مربی، گروه آموزشی هوشبری، دانشگاه علوم پزشکی نیشابور، نیشابور، ایران