fa ارتباط بین استئوآرتریت و استئوپروز در جمعیت بیماران مراجعه کننده به بیمارستان های شهرستان ساری ارتوپدی،تروماتولوژی Orthopedic & Traumatology پژوهشي-کامل Research(Original) <span style="font-size:12pt"><span style="line-height:115%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span b="" lang="AR-SA" style="font-family:" zar="">&nbsp;</span></b></span></span></span></span><span style="line-height:94%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="FA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">سابقه</span></span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt"> و هدف:</span></span></span></span> <span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">استئوآرتریت و استئوپروز از مهمترین عوامل </span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">ایجادکننده اختلالات اسکلتی بوده و ارتباط آن</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">‌</span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">ها با یکدیگر و سایر عوامل، موضوعی بحث برانگیز و مجهول می</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">‌</span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">باشد. </span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">مطالعه حاضر با هدف بررسی </span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">ارتباط بین </span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">استئوآرتریت و استئوپروز و نیز ارتباط بین این دو بیماری با مشخصات دموگرافیکی و سبک زندگی بیماران انجام پذیرفت.</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%"><span style="color:#0e101a"></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:94%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">مواد و روش</span></span></span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">‌</span></span><span lang="AR-SA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">ها:</span></span></span></span> <span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">مطالعه مقطعی حاضر به روش سرشماری بر روی بیمارانی که به </span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">بیمارستان‌های شهرستان ساری در 3 ماهه چهارم سال 1397 </span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">مراجعه کرده بودند، انجام گرفت. شدت استئوآرتریت پس از رادیوگرافی از مفصل زانو، براساس <span style="letter-spacing:-.1pt">معیار </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%"><span style="letter-spacing:-.1pt">Kellgren-Lawrence</span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt"> مشخص گردید. اندازه</span></span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">‌</span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">گیری سطوح </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%"><span style="letter-spacing:-.1pt">BMD</span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt"> نیز با روش </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%"><span style="letter-spacing:-.1pt">DXA scan</span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt"> انجام شد. ابزار جمع</span></span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">‌</span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">آوری</span></span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""> اطلاعات شامل پرسشنامه دموگرافیکی و ابعاد سبک زندگی بود. </span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%">SPSS-18</span></span> <span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">انجام گرفت.</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="color:black"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:94%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">یافته</span></span></span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">‌</span></span><span lang="AR-SA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">ها:</span></span></span></span> <span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">تعداد 77 بیمار مورد مطالعه قرار گرفتند که میانگین سن بیماران 10/3</span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:94%">&plusmn;</span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar="">57/3 سال و 73 نفر (94/8 درصد) زن بودند. از لحاظ شدت استئوآرتریت، 28 بیمار (36/36 درصد) نوع خفیف، 31 بیمار (4026/26 درصد) نوع متوسط و 18 بیمار (23/38 درصد) نوع شدید بودند. </span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">میانگین </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%">BMD</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar=""> در بیماران نیز 0/06</span></span><span lang="FA" style="font-size:10.0pt"><span style="line-height:94%">&plusmn;</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">0/76 <span style="background:white">گرم بر سانتی</span>‌<span style="background:white">متر مربع محاسبه شد. بین شدت استئوآرتریت و مقدار </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%">BMD</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar=""> اختلاف معنادار آماری وجود داشت (0/008</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%">=</span></span> <span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%">P</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">). بین این دو بیماری با سن، جنس، وزن و برخی از شاخص‌های سبک زندگی اختلاف معنادار آماری مشاهده شد (0/05 </span></span><span lang="FA" style="font-size:10.0pt"><span style="line-height:94%"><span b="" style="font-family:" zar="">></span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:94%">P</span></span><span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">).<span style="color:black"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:94%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:94%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">استنتاج:</span></span></span></span> <span lang="FA" style="line-height:94%"><span b="" style="font-family:" zar="">استئوآرتریت در مفصل زانو با بروز استئوپروز ارتباط دارد. در این راستا عوامل دموگرافیکی و سبک زندگی می‌توانند به عنوان مهم‌ترین عوامل تاثیرگذار در بروز این بیماری‌ها باشند.</span></span><span lang="AR-SA" style="line-height:94%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.2pt"></span></span></span></span></span></span></span></span></span></span></span><br> &nbsp; <span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b>&nbsp;</b></span></span><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:"><span style="letter-spacing:-.2pt">Background and purpose:</span></span></span></span></b><span lang="EN" style="font-size:10.0pt"><span style="line-height:150%"> Osteoarthritis and osteoporosis are the most important causes of skeletal disorders and there are controversies over the relationship between these diseases and other factors. The aim of the present study was to investigate the relationship between osteoarthritis and osteoporosis and also the association between these two diseases and patients&rsquo; demographic and lifestyle characteristics.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:150%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Materials and methods:</span></span></span></b><b> </b><span lang="EN" style="font-size:10.0pt"><span style="line-height:150%">This cross-sectional study was performed in patients attending Sari hospitals in the fourth quarter of 2019 selected via census sampling. Knee radiography was performed and the severity of osteoarthritis joint was determined based on Kellgren-Lawrence criterion. Bone mineral density (BMD) was also measured by DXA scan. Data was collected using demographic questionnaire and lifestyle dimensions. Data were analyzed in SPSS V18.</span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Results:</span></span></span></b><b> </b><span style="font-size:10.0pt"><span style="line-height:150%">A total of 77 patients were studied. The mean age of patients was 57.3&plusmn;10.3 years and the majority were females (n= 73, 94.8%). Severity of osteoarthritis was determined as mild in 28 (36.36%), moderate in 31 (40.26%), and severe in 18 (23.38%) patients. The mean BMD level was 0.76&plusmn;0.06 g/cm². There was a significant difference between the severity of osteoarthritis and BMD level (P=0.008). Significant differences were found between patients with osteoarthritis and osteoporosis in age, sex, weight, and some lifestyle indicators (P<0.05).</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:150%"><span style="vertical-align:top"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:">Conclusion:</span></span></span></b> <span lang="EN" style="font-size:10.0pt"><span style="line-height:150%">Osteoarthritis of the knee joint is associated with osteoporosis. But, demographic and lifestyle characteristics could have a major role in the incidence of these diseases.</span></span></span></span></span></span><br> <br> &nbsp; استئوآرتریت, استئوپروز, سبک زندگی osteoarthritis, osteoporosis, lifestyle 70 81 http://jmums.mazums.ac.ir/browse.php?a_code=A-10-3227-15&slc_lang=fa&sid=1 Davood Nasiry داود نصیری davood1990nasiry@gmail.com 1003194753284600145089 1003194753284600145089 No Assistant Professor, Department of Anatomy, Amol Faculty of Paramedicine, Mazandaran University of Medical Sciences, Sari, Iran استادیار، گروه علوم تشریح، دانشکده پیراپزشکی آمل، دانشگاه علوم پزشکی مازندران، ساری، ایران Masood Shayesteh Azar مسعود شایسته آذر mshayestehazar@mazums.ac.ir 1003194753284600145090 1003194753284600145090 No Associate Professor, Department of Orthopedic Surgery, Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran دانشیار، گروه ارتوپدی، مرکز تحقیقات ارتوپدی، دانشگاه علوم پزشکی مازندران، ساری، ایران Samira Andarkhora سمیرا اندرخورا sandarkhora92@gmail.com 1003194753284600145091 1003194753284600145091 No Medical Student, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran دانشجوی پزشکی، دانشکده پزشکی، دانشگاه علوم پزشکی مازندران، ساری، ایران Fereshteh Talebpour Amiri فرشته طالب پور امیری ftaleb2001@yahoo.co.uk 1003194753284600145092 1003194753284600145092 Yes Associate Professor, Department of Anatomy, Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran دانشیار، گروه علوم تشریح، مرکز تحقیقات بیولوژی سلولی و مولکولی، دانشگاه علوم پزشکی مازندران، ساری، ایران