fa بررسی اپیدمیولوژیک سرطان مری در جمعیت منتخب استان مازندران اپیدمیولوژی Epidemiology گزارش کوتاه Brief Report <span dir="RTL" lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">&nbsp;</span></span><span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:82%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="FA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">سابقه</span></span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt"> و هدف:</span></span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.2pt">نواحی شمالی ایران از بروز بالای سرطان مری برخوردار است. </span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.2pt">این</span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.2pt">مطالعه</span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.2pt">با</span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.2pt">هدف بررسی اپیدمیولوژیک</span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""> بیماران</span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">سرطان</span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">مری در</span></span> <span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar="">جمعیت تحت پوشش دانشگاه علوم پزشکی</span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">مازندران انجام</span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">پذیرفت</span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%">.</span></span><span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="color:#0e101a"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:82%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">مواد و روش</span></span></span></span><span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.1pt">‌</span></span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">ها:</span></span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">در این مطالعه توصیفی- مقطعی، پرونده‌های 170 نفر از بیماران بالای 18 سال مراجعه‌کننده به کلینیک فوق‌تخصصی انکولوژی طوبی طی سال‌های 1393 تا 1395 بازخوانی و </span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">کلیه اطلاعات شامل سن، جنس، شغل، وضعیت تاهل، میزان تحصیلات و یافته</span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">‌</span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">های بالینی و پاتولوژیکی بیماران پس از جمع‌آوری</span></span><span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar="">،</span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""> وارد نرم‌افزار </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%">SPSS</span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""> ورژن 22 شد. </span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">بررسی آماری با استفاده از آزمون‌های آماری </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%">Chi-square</span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""> و </span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%">Fisher&rsquo;s exact</span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">انجام گرفت.</span></span><span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="color:black"></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:82%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">یافته</span></span></span></span><span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.1pt">‌</span></span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.1pt">ها:</span></span></span></span> <span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">در بین افراد مبتلا با </span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">میانگین سنی 12 </span></span></span><span lang="AR-SA" style="line-height:82%"><span cambria="" style="font-family:"><span style="letter-spacing:-.1pt">&plusmn;</span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">68/2 سال بیش‌ترین فراوانی، مربوط به گروه سنی 70 تا 79 سال بود. 53/5 درصد مبتلایان مرد بودند. </span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">94/1 درصد بیماران </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%"><span style="letter-spacing:-.1pt">dysphagia</span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt"> داشتند. فراوانی (</span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%"><span style="letter-spacing:-.1pt">SCC</span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">) </span></span></span><span dir="LTR" style="font-size:10.0pt"><span style="line-height:82%"><span style="letter-spacing:-.1pt">Squamous cell carcinoma</span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">با </span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt">افزایش سن، افزایش داشت.</span></span></span><span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="letter-spacing:-.1pt"> هم‌چنین بیش‌ترین و کم‌ترین موارد متاستاز به ترتیب مربوط به بخش میانی و فوقانی مری بود.</span></span></span><span lang="FA" style="line-height:82%"><span b="" style="font-family:" zar=""><span style="color:black"><span style="letter-spacing:-.1pt"></span></span></span></span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:82%"><span style="direction:rtl"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><span lang="AR-SA" style="line-height:82%"><span b="" koodak="" style="font-family:"><span style="color:black"><span style="letter-spacing:-.2pt">استنتاج:</span></span></span></span> <span lang="AR-SA" style="line-height:82%"><span b="" style="font-family:" zar="">سرطان مری در سنین بالا شایع بوده </span></span></span></span></span></span></span></span></span><span dir="RTL" lang="AR-SA" style="font-size:12.0pt"><span b="" style="font-family:" zar="">و </span></span><span dir="RTL" lang="AR-SA" style="font-size:8.0pt"><span b="" style="font-family:" zar="">احتمالا سن عامل تاثیرگذار در وقوع آن بوده است.</span></span><br> &nbsp; <span style="font-size:12pt"><span style="line-height:140%"><span style="tab-stops:36.0pt"><span new="" roman="" style="font-family:" times=""><span style="font-size:10.0pt"><span style="line-height:140%"></span></span></span></span></span><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%"><span arial="" style="font-family:"><span style="letter-spacing:-.2pt">Background and purpose:</span></span></span></span></b> <span style="font-size:10.0pt"><span style="line-height:115%">The northern regions of Iran have a high incidence of esophageal cancer. This study was conducted with the aim of epidemiological investigation of esophageal cancer patients in the population covered by Mazandaran University of Medical Sciences.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:115%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%"><span arial="" style="font-family:">Materials and methods:</span></span></span></b><b> </b><span style="font-size:10.0pt"><span style="line-height:115%">In this cross-sectional descriptive study, the records of 170 patients over 18 years of age who were referred to Tuba Oncology Clinic (affiliated with Mazandaran University of Medical Sciences) between 2014 and 2016 were reviewed. All relevant information, including age, sex, occupation, marital status, level of education, clinical and pathological findings of patients were collected and analyzed in SPSS V22 using Chi-square and Fisher&rsquo;s exact test.</span></span></span></span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%"><span arial="" style="font-family:">Results:</span></span></span></b><b> </b><span style="font-size:10.0pt"><span style="line-height:115%">The mean age of patients with esophageal cancer was 68.2</span></span><span dir="RTL" lang="AR-SA" style="font-size:10.0pt"><span style="line-height:115%"><span cambria="" style="font-family:">&plusmn;</span></span></span><span style="font-size:10.0pt"><span style="line-height:115%">12 years. The disease was more frequent in patients aged 70-79 years old. There were 53.5% male patients and 94.1% of patients had </span></span><span style="font-size:10.0pt"><span style="line-height:115%">dysphagia. The frequency of squamous cell carcinoma (SCC) was found to increase by aging. The most and least metastatic segments were middle and upper parts of the esophagus, respectively.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span style="vertical-align:top"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%"><span arial="" style="font-family:">Conclusion:</span></span></span></b> <span style="font-size:10.0pt"><span style="line-height:115%">Esophageal cancer is common in old age and age is probably the most important factor in developing the disease.</span></span><i><span style="font-size:10.0pt"><span style="line-height:115%"></span></span></i></span></span></span></span><br> <br> <span style="font-size:12pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:150%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:150%"><span arial="" style="font-family:"><span style="letter-spacing:-.2pt">&nbsp;</span></span></span></span></b></span></span></span></span></span> سرطان مری, اپیدمیولوژی, دیسفاژی (dysphagia) esophageal cancer, epidemiology, dysphagia 143 147 http://jmums.mazums.ac.ir/browse.php?a_code=A-10-412-7&slc_lang=fa&sid=1 Zeinab Ghazizadeh زینب قاضی زاده 1003194753284600151667 1003194753284600151667 No PhD in Health Information Technology, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran دکتری تخصصی فناوری اطلاعات در سلامت، مرکز تحقیقات سرطان دستگاه گوارش، پژوهشکده بیماری‌ های غیر واگیر، دانشگاه علوم پزشکی مازندران، ساری، ایران Akbar Hedayatizadeh-Omran اکبر هدایتی زاده عمران akbar_hedayati@yahoo.com 1003194753284600151668 1003194753284600151668 Yes Associate Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran دانشیار، مرکز تحقیقات سرطان دستگاه گوارش، پژوهشکده بیماری‌های غیر واگیر، دانشگاه علوم پزشکی مازندران، ساری، ایران Reza Alizade Navaei رضا علیزاده نوایی 1003194753284600151669 1003194753284600151669 No Associate Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran دانشیار، مرکز تحقیقات سرطان دستگاه گوارش، پژوهشکده بیماری‌های غیر واگیر، دانشگاه علوم پزشکی مازندران، ساری، ایران Mahmood Moosazadeh محمود موسی زاده 1003194753284600151670 1003194753284600151670 No Associate Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran دانشیار، مرکز تحقیقات سرطان دستگاه گوارش، پژوهشکده بیماری‌های غیر واگیر، دانشگاه علوم پزشکی مازندران، ساری، ایران Ehsan Zaboli احسان زابلـی 1003194753284600151671 1003194753284600151671 No Assistant Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran استادیار، مرکز تحقیقات سرطان، دستگاه گوارش، پژوهشکده بیماری‌‌های غیر واگیر، بیمارستان امام خمینی، دانشگاه علوم پزشکی مازندران، ساری، ایران Leila Mirzakhani لیلا میرزاخانی 1003194753284600151672 1003194753284600151672 No Assistant Professor, Gastrointestinal Cancer Research Center, Non-communicable Diseases Institute, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran استادیار، مرکز تحقیقات سرطان، دستگاه گوارش، پژوهشکده بیماری‌‌های غیر واگیر، بیمارستان امام خمینی، دانشگاه علوم پزشکی مازندران، ساری، ایران Majid Saeedi مجید سعیدی 1003194753284600151673 1003194753284600151673 No Professor, Department of Pharmaceutics, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran استاد، مرکز تحقیقات علوم دارویی، دانشگاه علوم پزشکی مازندران، ساری، ایران Mina Mollaahmadi مینا ملااحمدی 1003194753284600151674 1003194753284600151674 No General Practitioner, Sari, Iran پزشک عمومی، ساری، ایران Arian Jahandideh آرین جهاندیده 1003194753284600151675 1003194753284600151675 No General Practitioner, Sari, Iran پزشک عمومی، ساری، ایران Majid YaghoubiAshrafi مجید یعقوبی اشرفی 1003194753284600151676 1003194753284600151676 No General Practitioner, Population-Based Cancer Registry, Mazandaran University of Medical Sciences, Sari, Iran پزشک عمومی، مرکز ثبت سرطان مبتنی بر جمعیت مازندران، دانشگاه علوم پزشکی مازندران، ساری، ایران Elahe Mahmoodi الهه محمودی 1003194753284600151677 1003194753284600151677 No MSc in Statistics, Population-Based Cancer Registry, Mazandaran University of Medical Sciences, Sari, Iran کارشناس ارشد آمار، مرکز ثبت سرطان مبتنی بر جمعیت مازندران، دانشگاه علوم پزشکی مازندران، ساری، ایران