2024-03-29T12:14:54+03:30 http://jmums.mazums.ac.ir/browse.php?mag_id=66&slc_lang=fa&sid=1
66-988 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Isolation of Bordetella Pertussis and Bordetella Parapertussis from Clinical Specimens at Different Provinces Fereshteh Shahcheraghi shahcheraghifereshteh@yahoo.com Masoumeh Nakhost Lotfi Masoumeh Parzadeh Vajihe Sadat Nikbin Fahimeh Shouraj Seyed Mohsen Zahraei Background and purpose: Bordetella pertussis is a gram negative and obligate aerobic bacteria that is cause of whooping cough and is exclusively a human pathogen. In the last decade increasing rate of pertussis was observed. Despite the importance of pertussis as a contagious disease enough information does not exist regarding its incidence rate in Iran. In this research pertussis suspicious specimens were collected from different provinces of Iran in 2009-2010 and then were studied. Materials and methods: A total of 1084 sample from nasopharyngeal secretion or nasal of patients with coughing more than two weeks were collected from different provinces of Iran and were sent to microbiology unit of pertussis reference laboratory in Pasteur institute of Iran. The isolation was done through culturing method. All samples were inoculated through swab on pertussis charcoal agar and Bordet-Gengou plates containing (40 µg/ml) cephalexin antibiotic and once without it. Then the suspected colonies were gram stained and complementary tests was done if colonies were identified as B. pertussis, B. parapertussis. Results: From the total of 1084 samples 12 inoculated samples were positive (1.1%) of which 11 samples were B. pertussis and one sample was B. parapertussis. Among positive cultures, three cases were the patients who were below 2 months, six cases related to individuals from two months to two years of age, two cases related to those aged between two and 10 years old and one patient was over 10 years of age. Nine cases of positive culture specimens were vaccinated and seven cases were the patients who used antibiotics. Conclusion: Results of this study indicated that most isolated strains in Iran were related to those aged between two months to two years old. According to clinical and paraclinical problems regarding whooping cough in Iran and also low sensitivity of culturing method to diagnose Bordotella, complementary methods such as Real-Time PCR should be used. Bordetella pertussis Bordetella parapertussis Culture 2012 5 01 2 8 http://jmums.mazums.ac.ir/article-1-988-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Investigating the Relationship between Eosinophilia and Coronary Artery Disease in Patients with Kawasaki Disease Mohhamad Sadegh Rezai Leila Shokohi Mohhad Jafar Saffar Aida Zeinali Ali Abaskhanian Snali45@yahoo.com Background and purpose: Kawasaki disease (KD) is an acute vasculitis in children. Studies indicated different relationships between eosinophilia and coronary artery disease (CAD). This study was done to assess the possible relationship between eosinophilia and coronary artery disease. Materials and methods: This descriptive study was carried out during 13 years on 61 children with Kawasaki disease who were admitted to Sina Referral Hospital. They were assessed regarding eosinophilia and coronary artery diseases. Data was evaluated by Fisher exact and t-test. Results: The research population included 61 patients of whom 33 (54%) were male and 28 (46%) were female with the mean age of 36.56 ± 23 months. Among the patients 85% were >5 years of age and eosinophilia was found in 28 cases (45.9%) and five patients (14.8%) were diagnosed with coronary artery disease. This disease was observed in 25% suffering from eosinophilia and in 6% of the cases without eosinophilia. However, there was no association among gender, eosinophilia and coronary artery disease. Also, no significant difference was found between age groups. Conclusion: Eosinophilia was not a risk factor or protective factor for CAD. However, the exact relationship could be determined if further multicentre studies are carried out. Kawasaki disease coronary artery eosinophilia pediatrics 2012 5 01 10 16 http://jmums.mazums.ac.ir/article-1-987-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Evaluation of Workers’ Exposure to Crystaline Silica Particles in Some Factories of Mazandaran Province mahmoud Mohammadyan Mohammadd Rokni Rokni123@yahoo.com Shahram Islami Abolghasem Fazeli Abstract Background and purpose: Workers' exposure to respirable silica particles especially free crystalline silica in workplace could result in some dangerous diseases such as silicosis or lung fibrosis. This study was carried out to evaluate the workers' exposure to free crystalline silica particles in some industries using the infrared spectrophotometery method. Materials and methods: In this cross sectional study respirable silica dust was collected from workers' breathing zone using personal sampling device and a cyclone separator with a PVC filter. Then samples containing silica were analyzed by infrared spectrophotometery method based on NIOSH method 7602. Results: The mean of exposure to respirable silica particles within the workers' breathing zone in four industries was considerably higher than the threshold limit value recommended by ACGIH. Workers' exposure to crystalline silica particles ranged from 0.03 mgm-3 to 0.57 mgm-3 and there was a significant difference between the mean of respirable particle concentrations within the workers' breathing zone. Conclusion: Individuals working in asphalt production, foundry, sand and gravel mining and brick manufacturing are exposed to crystalline silica particle more than the standard level. Hence, in order to prevent silica related diseases more emphasize on health and safety issues is of great importance. Keywords: Workers\' exposure crystalline silica Mazandaran spectrophotometery 2012 5 01 17 24 http://jmums.mazums.ac.ir/article-1-989-en.pdf
66-993 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Botulinum Toxin Injection in Children with Constipation Caused by Internal anal Sphincter Achalasia Hasan Karami Alireza Alam Sahebpour Kaveh Paknezhad Leila Shokohi2 shokohileila@gmail.com Soheila Shahmohammadi Abstract Background and purpose: To determine the effect of intrasphincteric botulinum toxin injection to treat internal anal sphincter achalasia. Materials and methods: Twenty patients (11 boys, average age 4.95± 2.47 years) with definite diagnosis of internal anal sphincter achalasia received 20 units of botulinum toxin injection in 4 points of the internal anal sphincter (totally 80 units). Then during 8 months of follow up visits, profile and response to treatment and bowel movements criteria of the patients were recorded in a questionnaire Results: All patients except one had treatment response. On 1-month follow-up, response to treatment was excellent in 35% of patients, and average in 60%. Response to treatment after 8 months follow-up was excellent in 50% and average in 40% and 10% was poor. The effect of botulinum toxin in 14 patients continued by the end of follow-up, and in 5 patients lasted between 7 to 20 weeks. The therapeutic response of these people, except one, remained moderate. Transient fecal incontinency was the only complication observed in 3 patients that was resolved after 1 to 3 weeks. Conclusion: Injection of botulinum toxin into the internal anal sphincter is an effective and safe method of treatment for achalasia, with long lasting results and few transient complications. Key words: internal anal sphincter achalasia botulinum toxin constipation pediatrics 2012 5 01 25 33 http://jmums.mazums.ac.ir/article-1-993-en.pdf
66-1072 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Comparing the Big Five Personality Factor in Patients with Multiple Sclerosis and Healthy Individuals Seyed Mahmoud Abedini psychologist_68@yahoo.com Sahar Montazeri Shohreh Ghorban Shiroudi Background and purpose: Multiple sclerosis (MS) is a chronic diseases of the nervous system in which the myelin nerve fiber in the brain and spinal cord is destroyed and the causes are still unclear. MS could result in progressive disabilities in young adults with different symptoms and incidence rate. This research aimed at comparing the big five personality factor in MS patients and healthy individuals. Materials and methods: This research was a case-control study which was conducted in east of Mazandaran. The research population included 191 patients with multiple sclerosis and 191 healthy individuals who were the patients’ companions with similar age, sex, marital status and education level with the first group. Personal questionnaire and NEO Personality Inventory-Revised were used and the data was analyzed by independent t-test. Results: The mean of neuroticism personality factor in patients and healthy subjects was 30.81 and 24.12, respectively (P= 0.001). Their means in conscientiousness were 30.9 and 35.93, respectively (P= 0.001). Conclusion: This study revealed that patients suffering from MS had a higher score in neuroticism personality factor and a lower score in conscientiousness compared with healthy subjects. Personality factor multiple sclerosis healthy individuals 2012 5 01 35 39 http://jmums.mazums.ac.ir/article-1-1072-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Qualitative Analysis of Coastal Waters in the Caspian Sea in Guilan Province: Determining the Environmental Health Indicators in Swimming Areas Masoud Binesh Barahmand binesh1348@yahoo.com Ramin Nabizadeh Kazem Nadafi Alireza Medzaghi nia Background and purpose: Guilan province, with unique environmental values is located in southwest of the Caspian Sea. Disposal of untreated domestic, industrial and agricultural sewage to the surface of water pollutes the coastal waters of the Caspian Sea. Due to many pollutants in these swages they could endanger the health of swimmers. The purpose of this study was to evaluate the microbial contamination of water in the Caspian shores of Guilan province. Materials and methods: In this study 21 littoral swimming areas in Guilan were studied regarding microbial contamination by microbial indicators of fecal and total coliform with pH, temperature and turbidity during 2009-2010. In each swimming area six samples were taken during the study period. The data from the total of 122 samples were analyzed using statistical software. Results: The results showed that the mean of total coliform and fecal coliform was 234.8 and 60 MPN per 100 ml, respectively. The mean of total coliform in swimming areas 1 and 2 were 1445 and 600 MPN per 100 ml, respectively. Fecal coliform in swimming areas 1, 2, 6, 8, 9 and 10, was 195.3, 163.5, 131.5, 111.7, 127.8, 118.8 MPN per 100 ml, respectively. Significant correlation was found among temperature, turbidity, and microbial contamination (P<0.05). Conclusion: The results indicated that the mean of total coliform in two swimming areas and the mean of fecal coliform in six swimming areas were more than the standard level. Therefore, these swimming areas are considered as a microbial threat to swimmers. Caspian Sea Guilan coastal waters microbial contamination total coliform fecal coliform 2012 5 01 41 52 http://jmums.mazums.ac.ir/article-1-992-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Reliability of Longus Colli Muscle Dimensions Measurement Using Ultrasonography in Healthy Subjects and Kjavanshir@yahoo .com Abstract Background and purpose: The deep cervical flexor muscles have a major role in neck stabilization and evidence suggests that these muscles especially longus colli muscle (LCM) becomes dysfunctional in panitents suffering from cervicogenic headache. Therefore, measurement of these muscles in healthy subjects and patients may be of great value to understand the stabilization function of the muscles and also to fallow the effect of interventions. The purpose of this study was to assess within and between days reliability of LCM anterior-posterior dimension(APD) and lateral dimension (LD) measurement using ultrasonography (US) in a group of healthy subjects and a group of patients with cervicogenic headache. Materials and methods: This methodological research was performed on 19 subjects including 10patients with cervicogenic headache and 9 healthy subjects. Neck LCM dimensions was measured at the level of thyroid cartilage using a real time US device. Two images of LCM dimensions were taken on the same day with an hour interval to assess the within- day reliability and the third image was taken tow days later to determine between- days reliability. Then data were compared using statistical analysis. Results: Healthy subjects were aged between 20-35 and patients between 20- 25 The ICC measurements for within day and between days reliability in healthy subjects were varied ranging from 0.80 to 0.92 for APD, 0.68-0.89 for LD. In patients group it was also ranged between 0.90- 0.92 and 0.81-0.90 respectively. The highest reliability score were performed for APD measurement in healthy subjects and patients with cervicogenic headache (ICC= 0.92). Conclusion: The results indicated that US could be a reliable tool to measure the LCM dimensions in healthy subjects and patients with cervicogenic headache. Therefore, this non invasive method can be used to follow up the effect of exercise therapy interventions. Key words: Ultrasonography Longus colli muscle cervicogenic headache Muscle dimensions Reliability longus colli muscle thickness longus colli muscle width 2012 5 01 58 64 http://jmums.mazums.ac.ir/article-1-995-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Effect of Ginkgo Biloba Pill on Patients with Major Depression Treated with Electroconvulsive Therapy Neda Parvin np285@yahoo.com Masoud Nikfarjam Iraj Goudarzi1 Salumeh Heidari Leyla Rafiee vardanjani Abstract Background and purpose: One of the most common complications of depression and treatment with ECT as one of the most effective treatments for depression is problem related to memory. This study was performed with aim of determination of the effects of Ginkgo pill on depression and cognition disturbance in this patients. Materials and methods: In this clinical trial study, 81 major depressed inpatients who was admitted in Hajar hospital allocated randomly in two groups (case and control). patients had indications of bilateral ECT. Before and at the end of treatment period with ECT, cognition status of patients was evaluated by Mini Mental State Exam questionnaire and depression severity was evaluated with Hamilton depression questionnaire. In case group, patients was treated with Ginkgo pill 40 mg each 8 hours and control group was treated with placebo for ECT treatment period (2weeks). Data analyzed by software SPSS 11 / 5 t-test, mean and ANOVA. Results: Between the two groups there was no statistically significant differences between age, gender, marital status, employment, duration of disease, depression and cognition score (P>0.05). The average scores in the field of cognitive problems and depression status of patients before and after ECT in both groups had significant difference (P<0.001) and case groups was better in both condition. Conclusion: Result of this study revealed the effectiveness of Ginkgo biloba in, cognition and depression status of major depress patients who treated with ECT, probably related to flavenoids and antioxidant component of this plant. Key words: Cognition depression ECT ginkgo biloba 2012 5 01 61 69 http://jmums.mazums.ac.ir/article-1-994-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Assessing the Dimensions of Semi-Spinalis Capitis Muscle and Isometric Strength of Cervical Extensor Muscles in Different Neck Positions in Healthy Female Individuals Asghar Reza Soltani Reza Nasiri ali Mohamad Feyzi Khodabakhsh Javanshir kjavanshir@yahoo.com Background and purpose: Ultrasonography is a reliable and valid method to assess the strength of neck extensors and measuring the neck muscles dimensions. Cervical muscles strength and dimensions may change in different positions. The aim of this study was to compare the strength of cervical extensor muscles and dimensions of semi-spinalis capitis muscle (SECM) in three different neck positions in healthy female individuals. Materials and methods: The research population included 30 female students, 18-24 years of age. Right SECM at the level of third cervical vertebrae was measured by ultrasonography in order to assess the isometric strength of neck extensor muscles in neutral, flexion and extension positions. The size of muscle was calculated by multiplying the anterior-posterior and lateral dimension of the muscle. Afterwards, the muscle strength was measured by a measuring device. One way-ANOVA was used to analyze the data. Results: The SECM size was significantly bigger in extension than that of the neutral and flexion positions (P<0.001). The strength of extensor muscles in neutral position was more than that of the flexion and extension positions. However, there was not a significant correlation between size and strength of the muscle in all three positions. Conclusion: The result of this study indicated that the size of SECM increased in extension position while the strength of neck extensor muscles decreased. The maximum performance of cervical extensor muscles appeared in neutral position of cervical spine, when the muscles were not maximally lengthened or shortened. Ultrasonography semi-spinalis capitis strength muscle size 2012 5 01 71 79 http://jmums.mazums.ac.ir/article-1-990-en.pdf
66-1089 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 The hepatotoxic and nephrotoxic effects of Stachys lavandulifolia Vahl in rat Ashi Taghikhani Roya Ansarisamani Hamid Afrogh Najmeh Shahinfard Furuzan Ganji Azam Asgari Fatemeh Taji Marziyeh Rahimi Samira Asgharzadeh Mahmoud Rafieian Background and purpose: Stachys lavandulifolia is used for many diseases. In this study the toxic effect of alcoholic extract of this plant was investigated, in rats. Materials and methods: In present experimental study, 100 Wistar rats (about 250gr, 8-12 weeks old) were divided into 10 groups randomly (8 groups as case and 2 groups as control groups). Alcoholic extract of Stachys lavandulifolia was prepared by maceration method. Normal saline was injected to control groups and doses of 50, 100, 150 and 200mg/kg of the extracts were injected to others groups, intraperitoneally, daily, for 28 days. In 29th day, and one month later, the serum parameters level (ALP, AST, ALT) and pathological samples were evaluated in different groups. Results: On the first month there was significant increase of AST level at dose of 200mg/kg and ALP level at all doses compared to the control group (P0.05). On the second month, the liver enzymes changes was almost the same as first month, exception for dose of 150mg/kg that was increased significantly in AST level compared to control group and in ALP level compared to dose of 100mg/kg (P<0.05). The main histological finding was necroinflammatory and fibrotic reactions in liver at all doses, compared to control group (P<0.001). On the first month this hepatic damages significantly increased at the higher doses (150 and 200mg/kg) compared to lower doses (50 and 100mg/kg) of the extract (P<0.05). Conclusion: Extract of Stachys lavandulifolia caused toxicity effect in rate's liver, and therefore it should be use with caution. Rat stachys lavandulifolia toxicity 2012 5 01 84 90 http://jmums.mazums.ac.ir/article-1-1089-en.pdf
66-1028 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 The Effects of Intera-Peritoneal Bupivacaine on Post Operative Bowel Motility and Pain Nasrin Rahmani Boeni mahdie@yahoo.com Mahdi abrahimi Ali Resa Khalilian Mina Alvandipour Sohrab Sayadi Background and purpose: The duration and intensity of intestinal motility disorder and pain following abdominal surgery vary among patients. Ileus and postportative pain are iatrogenic phenomena influencing the patients’ morbidity, hospital cost and length of stay in hospital. The aim of the present study was to determine the effect of intraperitoneal bupivacaine on postoperative bowel motility and pain. Materials and methods: A double-blind, randomized clinical trial was carried out on 120 candidates of abdominal surgery (appendectomy, cholecystectomy and laparatomy) aged between 15 and 80 years who referred to an educational hospital. The patients were randomly divided into two groups. Patients in case group, the patients received (1mg/kg) bupivacaine 0.5% in 20cc normal salin while the control group received only 30cc normal salin interaperitoneal. Afterwards, some information including nausea, vomiting, anorexia, distension, bowel sound, flatulence and defecation was recorded in six, 12, 18, 24 and 48 hours after surgery. Results: According to the results of this study the group receiving intraperitoneal bupivacaine intestinal motility happened 12-18 hours earlier (P=0.001) and severity of postoperative pain was reported less (P=0.001). Anorexia, vomiting and nausea also decreased in case group (P=0.002). Conclusion: This research indicates that intraperitoneal bupivacaine could reduce postoperative pain, vomiting, nausea, anorexia and may increase intestinal motility. Bupivacaine intraperitoneal intestinal motility postoperative pain 2012 5 01 89 94 http://jmums.mazums.ac.ir/article-1-1028-en.pdf
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Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Association of Preeclampsia with Lipid Concentration of Maternal Plasma and Umbilical Cord Shahnaz Barat Zahra Basirat zahra_basirat@yahoo.com Mehrdad Kashi fard Background and purpose: Preeclampsia is a medical condition in pregnancy that is determined by hypertension and proteinuria. Among many predisposing factors in pathophysiology of preeclampsia, the role of lipid peroxides is recently emphasized. The aim of this study was to evaluate the association of preeclampsia with maternal plasma and umbilical cord lipid concentration. Materials and methods: A case-control study was done on pregnant women referring to Babol Yahyanejad Hospital, during 2008-2009. Case group included 31 term preeclamptic pregnant women and for control group 31 term normal pregnant women were recruited. All women were 20-30 years of age and were gravida 1 or 2. Total TG, cholesterol, HDL and LDL for plasma and umbilical cord were measured by enzymatic and calorimetric methods. Results: No significant differences were found between women with preeclampsia and normal subjects according to the mean level of triglyceride (291.1  102.8 VS 309.4  114.4), cholesterol (226.3  48.8 VS 234.9  40.6), LDL (119  38.3 VS 123  33.1), HDL (50.1  10.6 VS 51.5  8.1) and VLDL (59.2  20.8 VS 61.5  22.6). Level of lipids in umbilical cord showed abnormal triglyceride level in only one case in the control group. Moreover, the mean level of umbilical cord triglyceride (56.3  32 VS 50.1  54), umbilical cord cholesterol (70.9  22.8 VS 64.4  20.8), umbilical cord LDL (30.9  12.7 VS 26.1  10), umbilical cord HDL (28.7  10.7 VS 30.7  8.6) and umbilical cord VLDL (11.6  6.8 VS 9.9  10.7) were not significantly different between preeclampsia and normal groups (P>0.05). Conclusion: Results showed that there was no association between lipid concentration of mothers and umbilical cord lipids with preeclampsia. Preeclampsia triglyceride cholesterol 2012 5 01 96 101 http://jmums.mazums.ac.ir/article-1-996-en.pdf
66-1029 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Comparing the Effects of Vitamin E and Fennel Extract on Intensity of Primary Dysmenorrhea Leila moslemi moslemi.Leila@ iausariac.ir. azar Aghamohammadi Reza Bekhradi Mandana Zafari Background and purpose: Primary dysmenorrhea is a common gynecologic problem among women. This study aimed at comparing the impacts of vitamin E and Fennel extract on intensity of primary dysmenorrhea. Materials and methods: A randomized single blind, placebo-controlled trial was carried out on 75 single female students who suffered from primary dysmenorrhea. They were divided into three groups receiving Fennel extract, vitamin E and placebo. Groups received treatment for two consecutive menstrual periods using the drugs four times a day from the onset of bleeding until three days. Results: Pain severity decreased in the Fennel extract (P0.05). Conclusion: Fennel extract which has few side effects could be used to treat primary dysmenorrhea. Primary dysmenorrhea fennel extract vitamin E 2012 5 01 103 107 http://jmums.mazums.ac.ir/article-1-1029-en.pdf
66-1070 2024-03-29 10.1002
Journal of Mazandaran University of Medical Sciences J Mazandaran Univ Med Sci 1735-9260 1735-9279 2012 22 88 Unusual Site of Recurrent Myxoma Originating in the Left Atrial Appendage Rozita Jalalian Ahmad Babaei Negin Akbari Myxoma is the most common type of primary tumors of heart. Recurrence of nonfamilial myxoma is unusual and recurrence in left atrial appendage is not reported. We present a case of sporadic myxoma in the left atrium who had a successful resection. However, the patient’s constitutional symptoms caused confusion and difficulty in diagnosis. Final diagnosis was recurrent Myxoma in the left atrial appendage which was made through echocardiography. Echocardiography is a standard choice for noninvasive diagnosis and localization of heart tumors. Operative resection of tumors is the most appropriate treatment for myxoma. Myxoma left atrial appendage recurrence 2012 5 01 109 112 http://jmums.mazums.ac.ir/article-1-1070-en.pdf