Volume 32, Issue 208 (4-2022)                   J Mazandaran Univ Med Sci 2022, 32(208): 94-101 | Back to browse issues page

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Babamahmoodi F, Heydari S, Shahabinia S, Mahdavi M R, Yazdani J, Davoodi L et al . Seroepidemiologic Survey of Hepatitis A in Mazandarani Pilgrims before Going to Karbala in Arbaeen Pilgrimage in 2018. J Mazandaran Univ Med Sci 2022; 32 (208) :94-101
URL: http://jmums.mazums.ac.ir/article-1-14607-en.html
Abstract:   (1035 Views)
 
Background and purpose: Recently, due to the reduction of hepatitis A in Iran there are people with low or no Hepatitis A Virus- Antibody (HAV-Ab), therefore, people at Arbaeen Pilgrimage are at risk for hepatitis A. This study aimed at examining HAV-Ab in pilgrims traveling from Mazandaran province, Iran to Karbala in 2018.
Materials and methods: This cross-sectional study was performed in 200 people selected from 40,000 pilgrims in Mazandaran province. Serum samples were evaluated for presence of HAV-Ab and data for demographic characteristics and history of hepatitis A immunity were recorded. Data analysis was performed in SPSS V16.
Results: The participants were 137 (68.5%) males and 63 (31.5%) females. Positive and negative HAV-Ab were seen in 156 (78%) and 44 (22%), respectively. Mean ages of people with positive and negative HAV-Ab were almost similar (50 years and 47 years, respectively). HAV-Ab status was found to be significantly associated with job (P<0.05) but it was independent of gender, level of education, area of residence, history of hepatitis A vaccination, previous history of hepatitis A infection, known underlying diseases, and history of travel to endemic areas (P>0.05).
Conclusion: Twenty-two percent of people who were travelling to Karbala had no HAV-Ab, which is significant because the risk of developing fulminant hepatitis increases in adults, therefore, vaccination of Karbala pilgrims for hepatitis A virus is suggested.

 
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Type of Study: Research(Original) | Subject: infection

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