Volume 32, Issue 212 (9-2022)
J Mazandaran Univ Med Sci 2022, 32(212): 97-106 |
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Jafari Sarouei M, Kamali M, Ghasemi Charati F, Shahbaznejad L, Hajalibeig A, Razavi-Amoli K et al . Epidemiological and Clinical Characteristics of Kawasaki Disease in Mazandaran. J Mazandaran Univ Med Sci 2022; 32 (212) :97-106
URL: http://jmums.mazums.ac.ir/article-1-18176-en.html
URL: http://jmums.mazums.ac.ir/article-1-18176-en.html
Mahboube Jafari Sarouei 
, Mahsa Kamali , Fahimeh Ghasemi Charati , Leila Shahbaznejad , Azin Hajalibeig , Kiana Razavi-Amoli , Mohammad Sadegh Rezai
, Mahsa Kamali , Fahimeh Ghasemi Charati , Leila Shahbaznejad , Azin Hajalibeig , Kiana Razavi-Amoli , Mohammad Sadegh Rezai
Abstract: (734 Views)
Background and purpose: Kawasaki is an acute childhood vasculitis of unknown cause that if left untreated can cause coronary aneurysms in 25% of cases. The disease is reported as the leading cause of acquired heart disease in children in developed countries. The purpose of this study was to investigate the epidemiological and clinical features of Kawasaki disease in northern Iran.
Materials and methods: In this descriptive-analytic review study, all registered cases of Kawasaki disease in Mazandaran province between 2007 and 2019 were investigated. Epidemiological, demographic, clinical, periodical tests, risk factors, disease burden, complications, and follow-up information were collected. Data analysis was done applying descriptive statistics, Chi-square test, and logistic regression.
Results: The data of 136 children with Kawasaki disease were assessed. Clinical symptoms were found to be significantly different between children with complete and incomplete Kawasaki disease (P<0.001). Most children with complete and incomplete Kawasaki disease had heart disease (63.2% and 75.5%, respectively), and coronary artery disease (52.6% and 58.2%, respectively) but no significant differences were found between the two groups in terms of cardiovascular involvement (P>0.05). Multivariate regression analysis showed that fever for more than 5 days is a predictor of coronary artery involvement (P= 0.001).
Conclusion: The study showed that fever for more than 5 days is a risk factor for heart and coronary artery involvement as one of the complications leading to death in these children. Therefore, accurate control of fever and heart examinations are important in children with symptoms of
Materials and methods: In this descriptive-analytic review study, all registered cases of Kawasaki disease in Mazandaran province between 2007 and 2019 were investigated. Epidemiological, demographic, clinical, periodical tests, risk factors, disease burden, complications, and follow-up information were collected. Data analysis was done applying descriptive statistics, Chi-square test, and logistic regression.
Results: The data of 136 children with Kawasaki disease were assessed. Clinical symptoms were found to be significantly different between children with complete and incomplete Kawasaki disease (P<0.001). Most children with complete and incomplete Kawasaki disease had heart disease (63.2% and 75.5%, respectively), and coronary artery disease (52.6% and 58.2%, respectively) but no significant differences were found between the two groups in terms of cardiovascular involvement (P>0.05). Multivariate regression analysis showed that fever for more than 5 days is a predictor of coronary artery involvement (P= 0.001).
Conclusion: The study showed that fever for more than 5 days is a risk factor for heart and coronary artery involvement as one of the complications leading to death in these children. Therefore, accurate control of fever and heart examinations are important in children with symptoms of
Type of Study: Research(Original) |
Subject:
Epidemiology
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