Volume 33, Issue 1 (11-2023)                   J Mazandaran Univ Med Sci 2023, 33(1): 314-320 | Back to browse issues page

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Abstract:   (323 Views)
Background and purpose: Human papillomavirus (HPV) infection is known as an important cause of invasive cervical neoplasms and carcinomas. The purpose of this study was to identify types of HPV in patients referred to Imam Khomeini Hospital in Sari with precancerous lesions and cervical cancer during 2013-2017
Materials and methods: This research is a descriptive-analytical retrospective cross-sectional study based on existing documents and files. In this study, for 5 years (2013-2017), 219 patients who underwent HPV DNA test and colposcopy and had premalignant and cancerous lesions were included in the study using the appropriate checklist. Data analysis was done using statistical tests, Chi-Square Test, One-Way ANOVA.
Results: In this study, the highest frequency was related to type 16 with the frequency of 73 (33.33%) people. Most of the patients had dysplasia in stages 1) CIN2, Cervical Intraepithelial Neoplasia 1 (CIN and CIN3) and were infected with one type of HPV. Also, 94 (44.76%) of the patients had normal pap smears and the highest frequency of abnormal pap smears with atopic squamous cells of undetermined significance (ASCUS) with a frequency of 43 (20%) and inflammation with a frequency of 36 (16.43%) were reported. In addition, 65 (30%) of the patients had a normal colposcopy and the highest frequency of colposcopies Abnormality was related to koilocytosis with a frequency of 76 (35%) and CIN 1 with a frequency of 67 (30.59%).
Conclusion: Since the HPV virus has no signs and symptoms, and considering the high prevalence of its high-risk type in this study in Iran and its relationship with cancerous and precancerous lesions, timely diagnosis and quick treatment are suggested to prevent the transformation of precancerous lesions to advanced cancer.
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Type of Study: Brief Report | Subject: Gynecology and Infertility

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