Volume 21, Issue 83 (Jul 2011)                   J Mazandaran Univ Med Sci 2011, 21(83): 74-78 | Back to browse issues page

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Gaeini A, Ghasemnian A, Dehkordi K, Kazemi A, Fallahi A. The Comparison of the Effect a Single Acute Exercise on Plasma, CRP, TNFα and IL-6 Levels in Immature Obese and Normal-weight Boys . J Mazandaran Univ Med Sci. 2011; 21 (83) :74-78
URL: http://jmums.mazums.ac.ir/article-1-692-en.html
Abstract:   (12628 Views)
Background and purpose: TNFα, ÇRP, and ÏL-6 are new cardiovascular inflammatory markers that an increase in their concentration results in an increase in cardiovascular diseases. This study is designed to compare the effect of a single acute exercise on plasma TNFα, ÇRP and ÏL-6 in immature obese and normal-weight boys.
Materials and methods: Â quasi-experimental study was designed and 21 healthy boy students of 11-14 years old were selected based on systematic randomization. Then, they were assigned into two groups of obese (77.07 ± 17.33 kg) and normal-weight boys (54.7 ± 8.28 kg). Âfter a five-minute warm-up, every participant started cycling on ergometer cycle with 65-70% of his maximum oxygen uptake (VÔ2 max) for 40 minutes, and then he ended his exercise with a five-minute cool-down. Blood samples were taken before, immediately and one hour after exercise to measure TNFα, HS-ÇRP, and ÏL-6 levels. Data were analyzed using the independent T-test, analysis of variance with repeated measures (R-ÂNÔVÂ) test, and the LSD post hoc test.
Results: Ït was shown that the level of ÇRP, TNFα, and ÏL-6 in obese boys were significantly higher than that of the normal-weight group in all three times of measurement (P<0.05).
Çonclusion: The results of this study showed that exercise with 65-70% of VÔ2 max can increase inflammatory factors in immature obese and normal-weight boys. Thus, exercise can stimulate their inflammatory and immune responses and increase the level of some of the mentioned markers.
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Type of Study: Research(Original) |

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