Soodabeh Vejdani-Aram, Javad Fardmal, Ghodratollah Roshanaei, Roya Najafi-Vosough, Hossein Mahjub, Ali Ghaleiha,
Volume 27, Issue 148 (5-2017)
Abstract
Background and purpose: Bipolar disorder is a mood disorder and mental illness that is recognized as type I and type II. Bipolar I disorder involves at least one episode of mania and is a common chronic recurrence disease with various causes responsible for its recurrence. The aim of this study was to determine effective factors on relapsing disease in patients with bipolar I disorder using frailty model.
Materials and methods: The information of 268 patients with bipolar I disorder who were hospitalized in Farshchian Hospital, Hamedan, Iran (2008-2014) were collected using their records. Patients hospitalized due to more than one recurrence were entered the study. The intervals between recurrence times were recorded. FrailtyPack of R software was used to fit model.
Results: The mean age of patients was 34.10±11.56 years, and 160 patients (72.7%) were male. In total, 696 recurrences occurred in 268 patients. The number of recurrences was between 2 to 7 times. All patients experienced at least 2 recurrence episodes. The results of fragmented frailty model practice showed significant effect of age, race, place of residence, crime, and type of treatment on relapsing time (P<0.05).
Conclusion: Many factors, including demographics and illness characteristics might cause the recurrence of bipolar disorder, therefore identifying these factors can help in preventing or reducing the incidence of recurrence of this disease.
Mohammad Fallah, Lotfollah Davoodi, Roya Najafi-Vosough, Mohammad Sardari, Shirafkan Kordi, Fariba Faizi, Leila Azarghoon, Abbas Ali Afrabandpey, Hassan Zare, Ali Akbar Shojaei, Eissa Soleymani,
Volume 31, Issue 203 (12-2021)
Abstract
Background and purpose: Toxocariasis is a zoonotic infection that can affect the human eye, some viscera, and even the nervous system. The infection is worldwide and is more prevalent in areas with poor hygiene such as rural areas. This investigation aimed at studying the seroprevalence of toxocariasis in Qaemshahr, north of Iran, for the first time, and recognizing its risk factors in rural areas.
Materials and methods: In this cross-sectional study, 370 people were selected from different rural areas and after completing a questionnaire, blood samples were collected. After isolation of serums, anti-Toxocara antibody was examined by ELISA kit (Novatec, Germany). Data were analyzed in SPSS V24 using logistic regression.
Results: Anti-Toxocara antibodies were detected in 159 (42.97%) patients. No significant association was observed between positive anti-Toxocara and variables studied (P>0.05). Among five selected areas, the rates of positive anti-Toxocara were significantly higher in two rural areas (P<0.05).
Conclusion: To the best of our knowledge, this study reported the highest seroprevalence of Toxocara in Iran. Physicians in this area are suggested to pay more attention to this infection. Due to the high seroprevalence of Toxocara in this region, further studies are required in other regions in Mazandaran province with a similar climate.
