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Background and purpose: Cardiopulmonary resuscitation is used for saving patients’ life and its success may increase by recognizing the aspects and factors influencing it. However, some factors are believed to be neglected. This study investigated the success of resuscitation in CPR team’s shift change. Material and Methods: During the study a total of 307 patients was under CPR and the outcome was successful in 78 cases and 20.5% of the patients discharged from hospital alive. The most popular diseases that resulted in CPR were internal diseases and cancers and the best result was obtained in poisoned cases. The rate of CPR was higher at night shifts, but there was no significant correlation between the time of shift change and the interval between these times and the outcome of CPR. Results: Our results are consistent with those of other studies in rate of success in CPR and suggest no relationship between this rate and the time of CPR team’s shift change. Conclusion: This study shown that CPR successfulness in emergency part of Imam Khomeini hospital is similar to other part of world and although changing time of CPR group's shifting is more critical, there are no statistical relationship with result of CPR