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Background and purpose: The purpose of this research was to compare the effects of aerobic exercises and green coffee consumption as a supplement on serum meteorin-like, myonectin level, and insulin resistance in obese women in Isfahan, Iran.
Materials and methods: A clinical trial was performed in 40 women who were randomly divided into four groups, including aerobic exercises (5 sessions per week/30-45 min/ 8 weeks), green coffee supplement (400 mg/daily), aerobic exercises (5 sessions per week/30-45 min/ 8 weeks) and green coffee supplement (400 mg/ 8 weeks), and control groups. Forty eight hr after the last exercise session, blood samples were collected (after a 12-hr overnight fast) to measure the serum meteorin-like, myonectin, insulin, and glucose levels. Data analysis was done applying dependent t-test and ANOVA.
Results: The participants’ mean weight, height, and BMI were 81.71±6.79 kg, 161.01±6.72 cm, and 32.4±4.6, respectively. ANOVA test showed significant differences in serum levels of myonectin
(P=0.001), meteorin-like (P= 0.007), insulin (P = 0.005), fasting glucose (P= 0.001) and insulin resistance (P=0.001) between the groups studied. Aerobic exercises and green coffee intake significantly increased serum myonectin and meteorin-like levels, compared to aerobic exercises (P= 0.001) and green coffee consumption alone (P= 0.001).
Conclusion: Green coffee intake and periodic exercises can affect some glycemic indices. Current study confirms the role of serum meteorin-like and myonectin level in preventing obesity and insulin resistance.
 
(Clinical Trials Registry Number: IRCT20170510033909N5)
 

Keywords: aerobic exercises, myonectin, meteorin-like, obesity, insulin resistance, green coffee

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