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Hollow fiber membrane contactors have been applied in various industries e.g. chemistry, petroleum, biotechnology and medicine. They are also widely used in artificial organs e.g. artificial lung, kidney and liver as well as some pharmaceutical procedures such as separation and purification of biological materials. Intrinsic properties of hollow fiber membranes, such as high packing density and high mass transfer rate have increased the use of these membranes. In tissue engineering, using such membranes is of great importance for membrane bioreactors and culturing of cells sensitive to stress and those which require high mass transfer rates. This article comprehensively investigates the use of the hollow fiber membrane contactors applied in advanced medical sciences and pharmaceutics. Their composition materials in addition to the important factors affecting their performance characteristics are also discussed.

Keywords: Membrane contactor, hollow fibers, bioreactor, artificial organ, tissue engineering, pharmaceutics

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