Volume 29, Issue 177 (10-2019)                   J Mazandaran Univ Med Sci 2019, 29(177): 91-98 | Back to browse issues page

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Alvandipoor M, Mahdavi A, Nouri B. Influence of Diosmin on Post hemorrhoidectomy Pain: A Si gle-blind n Randomized Controlled Trial. J Mazandaran Univ Med Sci. 2019; 29 (177) :91-98
URL: http://jmums.mazums.ac.ir/article-1-10800-en.html
Abstract:   (1006 Views)
Background and purpose: Fear of pain is one of the main reasons for refusing surgical hemorrhoidectomy among patients with hemorrhoids. This study investigated the effect of Diosmin on post-hemorrhoidectomy pain.
Materials and methods: A single-blind randomized clinical trial was performed in 92 patients undergoing hemorrhoidectomy. They were randomly divided into two groups; the intervention group (n=46) received Diosmin 500 mg daily, and the placebo group (n=46) received a tablet daily. Both groups were examined after a week. Duration of hospitalization, return to work, and time of complete recovery and pain were also examined. Data analysis was done in SPSS V18.
Results: The mean age of patients was 37.55±12.21 years. In both groups, distribution of population was completely homogeneous in terms of age (0.833), gender (1.00), degree of hemorrhoids (0.538), mucous secretion (0.514), duration of hospitalization (0.821), return to work (0.754), complete recovery (0.631), and postoperative bleeding (0.557) showing no significant relationship between the two groups (0.557). The mean pain intensity was 3.41±1.292 in intervention group and 4.65±1.370 in the placebo group which showed a significant difference between the two groups after the intervention (P=0.000).
Conclusion: Diosmin can be used as a safe drug with minimal side effects to control post-hemorrhoidectomy pain.
(Clinical Trials Registry Number: IRCT20180717040509N1)
Full-Text [PDF 542 kb]   (181 Downloads)    
Type of Study: Research(Original) | Subject: Nursing Education

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