Volume 22, Issue 97 (2-2013)                   J Mazandaran Univ Med Sci 2013, 22(97): 231-236 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Assessing Prevalence and Characteristics of Neuroendocrine Tumors in Patients in Imam Khomeiny Hospital (Referral Centre) in Tehran During 2004-2010. J Mazandaran Univ Med Sci. 2013; 22 (97) :231-236
URL: http://jmums.mazums.ac.ir/article-1-1818-en.html
Abstract:   (8758 Views)
Background and purpose: Incidence of neuroendocrine tumors in the world is increasing during these years. These tumors have a high complexity in clinical presentation, tumor stage and grade. In addition, using of markers like Ki67 level could help to estimate tumor grade. Assessing hospital prevalence of neuroendocrine tumors, Their origin and association between pathology and immunohistochemistry with Ki67 level was the purpose of conducting this study. Materials and methods: All patients’ records during 2004-2010 were reviewed to select patients with neuroendocrine diagnosis, then their pathology and histochemistry samples were examined again. Patients’ characteristics in addition to type, grade and origin of tumors were entered to check list. Results: Incidence of neuroendocrine tumors was 8 in 1000 patients. Data was gathered from 189 patients with neuroendocrine tumor diagnosis. Mean age was 49/6 years and Prevalence of each sex was 52/9% and 47/1% in men and women respectively. Pathology diagnoses were Carcinoid (27%), Round cell tumor (21.2%) and undifferentiated carcinoma (18.5%). Mean of Ki67 levels were significantly different by tumor grade, location, necrosis, pathology and immunohistochemistry. Conclusion: Based on this study, using Ki67 marker is helpful for diagnosing and determining tumor status, which could be effective on choosing the type of treatment.
Full-Text [PDF 141 kb]   (61892 Downloads)    
Type of Study: Research(Original) | Subject: Health Education

Add your comments about this article : Your username or Email:
Write the security code in the box

© 2018 All Rights Reserved | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb