Volume 18, Issue 66 (Oct 2008)                   J Mazandaran Univ Med Sci 2008, 18(66): 26-34 | Back to browse issues page

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Shafaat A, Shahrivar Z, Alaghband rad J, Kaviani H. Compare the efficacy of lithium carbonate & sodium valproate in treatment of bipolar children and adolescents in acute phase (mixed &mania) treatment at Roozbeh hospital . J Mazandaran Univ Med Sci. 2008; 18 (66) :26-34
URL: http://jmums.mazums.ac.ir/article-1-507-en.html
Abstract:   (12852 Views)
Background and Purpose: To compar the efficacy of lithium carbonate &sodium valproate in treatment of bipolar children and adolescents in acute phase (mixed &mania) in 6 week treatment at Roozbeh hospital .
Materials and methods: A double-blind & randomized controlled clinical trial in 30 patient (8-18 years) for a 6 week trial .patients were diagnosed based on DSM_IV criteria through clinical interview & K_SADS .MRS & CGAS were used to measure the severity of symptoms and the level of functional impairment .patients categorized into 2 groups randomly.
Results:In both groups means of MRS decreased (at the end of 3rd&6th weeks) and there was no significant difference between two groups. Means of CGAS had significant difference between two groups at 3rd week (p
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Type of Study: Research(Original) |

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