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Background and purpose: Appropriate and efficient disinfection is an important aspect of hospital infections control. The aim of this study was to investigate the effects of common disinfectants used for Escherichia coli bacteria separated from two teaching hospitals in Sari, 2014. Materials and methods: Escherichia coli were taken from different wards in Zare and BouAli hospitals. E.Coli was identified by standard plant methods, differential test and biochemical isolation. Deconex plus53, Creolin and Cidex were used as disinfectants in various concentrations. Their effects were determined by Standard disc diffusion method. Data was analyzed using regression in Minitab V.17. Results: A total of 120 samples were investigated of which 48 (40%) were found contaminated and 15 (13%) of these isolates were positive for E.coli. The most effective disinfectants against E.coli were Cidex 2%, deconex Plus53 2%, and Creolin 3.5%, respectively. Conclusion: Performing pretests is necessary for choosing the most appropriate disinfectant and increasing its efficacy. Also, it is important to consider common infectious bacteria in hospitals and effective factors on disinfectants such as concentration and time.

Keywords: Disinfectants, Nosocomial infections, Deconex 53plus, Cidex, Creolin, Escherichia coli

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