Volume 21, Issue 86 (Feb 2012)                   J Mazandaran Univ Med Sci 2012, 21(86): 168-173 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Habibi M R, Masoomi S, Godazandeh G A, Emadi S A, Akhbari P, Nooraee S M. The Effect of Magnesium Sulphate on Postoperative Pain and Opioid Consumption in Inguinal Hernia Surgery. J Mazandaran Univ Med Sci. 2012; 21 (86) :168-173
URL: http://jmums.mazums.ac.ir/article-1-862-en.html
Abstract:   (25091 Views)
Background and purpose: Although some studies have demonstrated the effect of magnesium sulphate on reducing the postoperative pain, some others have refuted this and showed that it has limited or no effect. In this study, the researchers investigated the effects of pre- and intraoperative magnesium sulphate administration on the postoperative pain and opioid consumption. Materials and methods: In a randomized double blind placebo controlled clinical trial, thirty-two patients with the age range of 15-74 undergoing inguinal surgery in Imam Khomeini Hospital in Sari were nonrandomly divided into two equal groups. The patients in the magnesium sulphate group received magnesium sulphate 50 mg/kg/h IV, 15 minutes before until one hour during the surgery, whereas patients in the control group received the same volume of normal saline 20cc (infusion with similar volume) over the same time. The data were analyzed using SPSS version 16. Results: Postoperative pain was significantly lower in magnesium sulphate group in comparison to control group. At 0, 2, 6, 12 and 24 hrs after the operation, the mean VAS for control and case groups were 8.50 ± 0.894, 7.06 ± 1.94, (P=0.012), 8.31 ± 1.07, 6.63 ± 1.360 (P=0.001), 8.06± 1.124, 4.75± 1.125 (P=0.001), 7.31 ± 1.45, 4.06 ±0.85 (P=0.001), 6.69 ±1.40, 0.63 ± 1.02 (P=0.001), respectively. Conclusion: Intraoperative magnesium sulphate infusion in inguinal surgery considerably decreases postoperative pain in the first 24 hours after operation. (Clinical Trials Registry Number: IRCT138809282883N1)
Full-Text [PDF 279 kb]   (2682 Downloads)    
Type of Study: Research(Original) |

Add your comments about this article : Your username or Email:

Send email to the article author

© 2020 All Rights Reserved | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb