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Background and purpose: Hypercholesterolemia and the activity of haemostatic factors may trigger cardiovascular diseases. Allium hirtifolium Boiss (Persian shallot) has been shown to have cardioprotective effects. This study evaluated the effects of A. hirtifoliumon on factor VII and serum fibrinogen levels in hypercholesterolemic rabbits. Also, the antioxidant capacity of A. hirtifolium was measured. Materials and methods: In an experimental study, 24 NewZealand male rabbits were randomly assigned into three groups of eight. The groups' diet which was followed for 60 days included normal diet, hypercholestrol diet (1%) or hypercholestrol diet (1%) + A. hirtifolium. The blood fibrinogen and factor VII were measured pre and post study in all groups. The A. hirtifolium antioxidant capacity was measured using beta-carotene linoleate. Results: The study showed that serum fibrinogen level and factor VII increased significantly in hypercholesterolemic group (329.22 ± 26.7 and 277.7 ± 17.1 mg/dl) compared to normal diet group (287.25 ± 13.7 and 230.0 ± 18.2 mg/dl), respectively (P<0.05). The amount of serum fibrinogen and factor VII decreased in hypercholesterol+A. hirtifolium group (180.0 ± 23.9 and 237.0 ± 53.3 mg/dl) compared to hypercholesterol diet group (P<0.05). The antioxidant capacity of A. hirtifolium extract was 52.1 ± 3.3% in 0.2 g/L. The plasma antioxidant capacity in the group fed with hypercholesterol + A. hirtifolium was 943.907 ± 249.51 µM which was higher compared to that of the normal diet group (629.675 ± 130.73 µM). Conclusion: A. hirtifolium decreases serum fibrinogen level and factor VII, therefore, it might be helpful in reducing risk factors of cardiovascular diseases. These influences are of great importance in patients with haemostatic disorders.

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Germ cell tumors account for 2 to 3% of all cancers in children. These tumors appear in the testicles as painless masses. The primary treatment of these tumors is the removal of testicles and chemotherapy. Giant cell tumor of the tendon sheath (GCTTS) is slow-growing tumor and the primary treatment of this tumor is surgery and both surgery and radiotherapy in invasive type. This report presents the case of a 7-year-old boy who was diagnosed with germ cell tumor at the age of 8 months. He had undergone surgery and chemotherapy and had recovered. At the age of 7, the patient referred with a mass in right heel and after evaluation and surgery, he was diagnosed with Giant cell tumor of the tendon sheath. Surgery was performed and no evidence of recurrence was observed in follow-up evaluation. To the best of our knowledge, this report is the first case of a giant cell tumor of the tendon sheath following the treatment of testicular germ cell tumor.

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Background and purpose: Intraventricular hemorrhage (IVH) is known as a major complication
of Prematurity. In this study, we aimed to examine complete blood count (CBC) variables in preterm infants with IVH.
Materials and methods: In this cross-sectional descriptive study, we studied preterm infants less than or equal to 34 weeks and less than 1500 g admitted to the NICU and neonatal ward of Bu Ali Sina and Imam Khomeini hospitals in Sari from 1395 to 1398.  The presence of IVH in brain ultrasonography was recorded in these neonates.
Results: Out of 367 neonates, 49.05% were boys and 50.95% were girls. The mean gestational age was 30.96±2.30 weeks and the mean weight of the patients was 1461±504.99 g. 41 patients (11.17%) had intraventricular hemorrhage. Infants with a history of maternal diabetes were more common in the group with intraventricular hemorrhage (P= 0.042). Mean hemoglobin, MCV and MCH were significantly higher in the group with ventricular hemorrhage and mean CRP and blood glucose were higher in this group (P<0.05). The results of logistic regression model showed that Higher blood sugar in the newborn, history of diabetes in the mother, history of receiving surfactant in the newborn, and lower MCH and MCV in the newborn baby's CBC were significantly effective in he chance of intraventricular hemorrhage (P<0.05). Also, hemoglobin and MCH were significantly lower in grades 2, 3 and 4 than grade 1of IVH.
Conclusion: Results of the present study showed that Microcytic hypochromic anemia can be used to predict the occurrence of IVH.