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Showing 3 results for Hosseininejad

Seyed Mohammad Hosseininejad, Abolhasan Khaje Samakoush, Seyed Hosein Montazer, Iraj Goli Khatir, Fatemeh Jahanian, Hamed Amini Ahidashti, Farzad Bozorgi, Jamshid Yazdani Charati, Hossein Asgarirad,
Volume 26, Issue 143 (12-2016)
Abstract

Background and purpose: IV opioids and nonsteroidal anti-inflammatory drugs are commonly used to control pain in renal colic. Buprenorphine is a drug that is recently introduced for such cases. The aim of this study was to compare the effect of sublingual buprenorphine and intravenous morphine to control pain in acute renal colic.

Materials and methods: A randomized double-blind, placebo controlled clinical trial was performed in 203 patients with acute renal colic. The samples were divided into two groups to receive either 2 mg sublingual buprenorphine and 5cc IV distilled water (experimental group) or intravenous morphine 0.1 mg/kg and a sublingual placebo (control group). Pain reduction and drug side effects were compared between the two groups. Data analysis was conducted in SPSS ver.22 using repeated measures, Chi-square, and t-test. 

Results: The participants included 79 (38.9%) females and the mean age of the patients in experimental and control groups were 40.50±13.50 and 39.85±13.66, respectively (P=0.73). The mean time required for pain improvement after drug administration was 30.97±19.92 min in experimental group and 34.87±18.59 min in controls (P= 0.19). Significant decrease in pain severity was observed in both groups (P< 0.001) but the type of drug had no significant effect in reducing pain (P= 0.25). Side effects were similar in two groups except for itching that was significantly higher in patients receiving buprenorphine (P= 0.007).

Conclusion: The efficacy of buprenorphine in treatment of renal colic was found to be similar to that of intravenous morphine. Side effects were also similar in two groups except itching that was significantly more prevalent in experimental group.

(Clinical Trials Registry Number: IRCT2015082023696N1)


Seyed Hossain Montazer, Motahareh Kheradmand, Reza Alizadeh-Navaei, Seyed Mohammad Hosseininejad, Ensiyeh Taghizadeh,
Volume 28, Issue 166 (11-2018)
Abstract

Background and purpose: Metoclopramide is frequently used in emergency departments to control nausea, vomiting, and headache. This study aimed at comparing the effects of two rates of intravenous infusion of metoclopramide (slow and fast bolus) on the incidence of akathisia in patients with cancer in an emergency department.
Materials and methods: In a double blind clinical trial, 112 patients with cancer hospitalized in Sari Imam Khomaini emergency department were included. The participants were randomized to receive either 20 mg metoclopramide as a bolus and normal saline infusion over 20 min (bolus group), or normal saline bolus and 20 mg metoclopramide infused over 20 min (infusion group). Patients were assessed for akathisia using the Prince Henry Akathisia Rating Scale. Nausea, sedation, pulse, and blood pressure were measured in both groups at 0, 30, 60, and 120 min after drug administration.
Results: The mean ages of patients in bolus and infusion group was 59.4 ± 16.1 and 60.3 ± 14.2, respectively. Frequency of women in bolus and infusion group was 48.3 and 56.1%, respectively. Objective akathisia in patients receiving bolus metoclopramide was 4 times more than that in infusion group. (P=0.000) (RR: 4, CI: 95%: 1.8-6.5). Trend of sleepiness was not significantly different between the two groups (P=0.625). But, the trends of nasaue, pulse, and hypertension showed significant differences between blouse and infusion groups. (P=0.000 and P=0.000, respectively).
Conclusion: Current findings showed that intravenous infusion of metoclopramide could reduce objective akathisia and nausea.
 
(Clinical Trials Registry Number: IRCT20170808035565N2)
 
Iraj Golikhatir, Fatemeh Jahanian, Seyed Mohammad Hosseininejad, Leila Asadian, Seyed Hosein Montazer,
Volume 29, Issue 178 (11-2019)
Abstract

Epiploic appendagitis is one of the self-limiting rare causes of acute abdominal pain that is caused by torsion or accidental necrosis of one of the epiploic appendix of the colon. Due to the absence of specific clinical findings for this disease, it is usually diagnosed by chance in examinations for the cause. The use of radiologic methods in diagnosis is very helpful. The importance of the topic is that, with appropriate diagnosis, unnecessary surgeries are prevented and the patient will fully recover with conservative treatment. This study introduces a 32-year-old man attending emergency department in Sari Imam Khomeini Hospital because of acute lowe left abdominal pain. In examination abdominal tenderness was found in the superficial and deep palpation of the left lower quadrant of the abdomen. Ultrasound scan showed an echogenic mass without vascular flow adjacent to the descending colon. Also, CT scan revealed an ipsilateral fat-density elliptical lesion along the sigmoid colon with fat stranding around the lesion without increase in thickness of the adjacent intestinal wall. The findings were diagnostic of epiploic appendagitis, and the patient's symptoms improved with medical treatment. According to this report, epiploic appendagitis should be considered in differential diagnosis of abdominal pain in relatively young patients with acute abdominal pain.
 

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