Showing 2 results for Jahandideh
Alireza Jahandideh, Abolfazl Akbarzadeh, Neda Vakili Moghadam, Parham Ziabakhsh Tabari, Negin Sadat Erfani,
Volume 29, Issue 175 (8-2019)
Abstract
Background and purpose: Some native species of medicinal plants are abundantly found in Iran. High incidence of ulcers in diabetic patients necessitates research on herbal medicines with fewer side effects. This study was conducted to evaluate the histological variables of the Fumaria parviflora extract on the repair of ulcers in diabetic rats.
Materials and methods: The study was carried out in 48 adult male Wistar rats at 14-15 weeks of age, weighing 200 ± 10 gr. Diabetes was induced by injection of alloxan. The animals were randomly divided into 4 groups (n= 12), including negative control group (healthy without any treatment), positive control group (diabetic with no treatment), experimental group I (diabetic treated by eucerin cream), and experimental group II (diabetic treated by a cream containing 3% F. parviflora). Histopathological examination was done at the end of days 3, 7, 14, and 21. The size of the scars and tissue indices were measured in these groups.
Results: There was a significant difference between the experimental group II and other groups in the rate of recovery (P <0.001). Compared to experimental group I, the scores for some microscopic parameters were higher in experimental group II.
Conclusion: According to current study, topical use of F. parviflora could diminish inflammation and accelerate wound healing. It was also found to be highly efficient in accelerating the transition from inflammatory to fibroblast hyperplasia phase. Therefore, F. parviflora as an efficient low-cost herbal medicine could be used in accelerating wound healing.
Zeinab Ghazizadeh, Akbar Hedayatizadeh-Omran, Reza Alizade Navaei, Mahmood Moosazadeh, Ehsan Zaboli, Leila Mirzakhani, Majid Saeedi, Mina Mollaahmadi, Arian Jahandideh, Majid Yaghoubiashrafi, Elahe Mahmoodi,
Volume 32, Issue 217 (1-2023)
Abstract
Background and purpose: The northern regions of Iran have a high incidence of esophageal cancer. This study was conducted with the aim of epidemiological investigation of esophageal cancer patients in the population covered by Mazandaran University of Medical Sciences.
Materials and methods: In this cross-sectional descriptive study, the records of 170 patients over 18 years of age who were referred to Tuba Oncology Clinic (affiliated with Mazandaran University of Medical Sciences) between 2014 and 2016 were reviewed. All relevant information, including age, sex, occupation, marital status, level of education, clinical and pathological findings of patients were collected and analyzed in SPSS V22 using Chi-square and Fisher’s exact test.
Results: The mean age of patients with esophageal cancer was 68.2±12 years. The disease was more frequent in patients aged 70-79 years old. There were 53.5% male patients and 94.1% of patients had dysphagia. The frequency of squamous cell carcinoma (SCC) was found to increase by aging. The most and least metastatic segments were middle and upper parts of the esophagus, respectively.
Conclusion: Esophageal cancer is common in old age and age is probably the most important factor in developing the disease.
