Showing 5 results for Janbabaee
Ghasem Janbabaee, Farshad Naghshvar, Tooraj Farazmandfar, Mostafa Salehi, Masoomeh Rashidi,
Volume 22, Issue 92 (8-2012)
Abstract
Background and purpose: Mortality rate from gastric cancer is growing in the world. Nowadays, in many cancers, between cancer development and changes in EGF receptor expression levels there is a very precise relationship. Perhaps one of the best known of these changes in gastric cancer is over expression of Her1 & 2 receptors. This study investigated the expression rate of these two receptors in gastric locally advanced adenocarcinoma, and its correlation with survival of patients.
Materials and methods: The samples include 130 paraffin blocks of patients with gastric cancer in Imam Khomeini Hospital in Sari 1383-88. 4 micron sections of tissue blocks were prepared and placed on slides. Then slides were deparaffinized with xylene and dehydrated using alcohol. The endogenous peroxidase activity was inhibited. Her2 Antibody is located on them. Finally, they were stained with hematoxylin.
Results: Her1 marker only in 23 samples (17.6 %) and Her2 marker only in 20 samples (15.4 %) were positive. Accompanying these two markers in 9 patients (6.9 %) was also seen simultaneously. The survey marker Her2 based on sex revealed in 91 male patients, only in 11 cases (11.6 %) and in 39 women only 9 cases (23 %) were positive
Conclusion: Expression levels of Her1 marker increased with increasing disease stage. These findings may indicate the diagnostic value of this marker in patients with gastric adenocarcinoma. Probably, the rate of HER1 and HER2 receptors expression is associated with invasion and survival of patients.
Ghasem Janbabaee, Mahmood Moosazadeh, Reza Agah, Soghra Khani, Asghar Nezammahalleh, Mohammad Fallah,
Volume 25, Issue 134 (3-2016)
Abstract
Background and purpose: Investigating and forecasting the different methods of labor can improve the knowledge about health problems in the future and the ability to develop effective interventions and prepare relevant resources. This study aimed at determining the trend and forecasting for cesarean section (c-section) and natural child birth in Mazandaran province, Iran.
Materials and methods: A longitudinal study was performed using all registered data regarding labors in governmental and private maternities in Mazandaran province. The number of childbirth from 2007 to 2014 were entered into SPSS 16 software. The best model was selected based on autocorrelation and partial autocorrelation diagrams in Ljung-Box significance level as well as the least AIC.
Results: The corresponding figures for 2007 to 2021 for cesarean and natural child birth were 19245, 15770 and 14382, 16385, respectively. The growth rate in private sectors was 17.7% (from 2007-2008). These rates were also observed to be 5.8% and 12.3% in 2013 and 2014, respectively. The results of forecasting revealed delivery growth in private sectors until 2021.
Conclusion: The c-section rate would decrease to 35% in 2021 if the healthcare reform interventions continue. This rate is still much more than the optimal c-section rate recommended by World Health Organization
Ghasem Janbabaee, Mahmood Moosazadeh, Zahra Asdaghi Jahrom, Masoumeh I Rashedi Alashti,
Volume 25, Issue 134 (3-2016)
Abstract
Background and purpose: Breast cancer is the most common cause of cancer-specific mortality among women worldwide. This study aimed at investigating the epidemiological, clinical, and pathological characteristics of breast cancer among patients attending Baghban Clinic in Sari.
Materials and methods: The patients’ records (2008-2014) were used and data including age, gender, marital status, menopausal status, pregnancy and breast feeding, tumor size, type of tumor, number of involved lymph nodes, and metastasis were collected using a researcher-made checklist.
Results: The study population included 1019 patients (mean age: 50.1± 11.5 years) with breast cancer. The menarche age was 12-16 years in 77.8% of the patients. About 61.5% of patients had been diagnosed with breast cancer before menopausal age. The first pregnancy of 6.6% of the patients occurred after 30 years of age. Familial history of cancer was reported in 237 patients, 65.4% of which were breast cancer. The most common type of breast cancer was ductal carcinoma (90.7%) with moderate differentiation among 61% of the patients. The mean tumor size was significantly higher among patients that underwent total mastectomy compared to those with history of partial mastectomy (7.7±1.4 vs. 7.4±1.6, P=0.008).
Conclusion: Our study showed ductal carcinoma as the most common type of breast cancer among studied women and tumor size was found to be one of the main factors associated with total mastectomy.
Siavosh Abedi, Ghasem Janbabaee, Mahmood Moosazadeh, Masoumeh Rashedi Alashti, Reza Alizadeh-Navaei, Akbar Hedayatizadeh-Omran,
Volume 27, Issue 151 (8-2017)
Abstract
Background and purpose: Lung cancer is a public health problem worldwide. Identifying the epidemiological characteristics of involved patients can play an important role in designing analytical studies. The aim of this study was to identify the epidemiology of patients with lung cancer attending Tooba clinic and Imam Khomeini Hospital in Sari, Iran.
Materials and methods: In this descriptive study, a sample size of 229 patients with lung cancer were chosen using census sampling. SPSS V22 was used for data analysis applying descriptive and analytic tests.
Results: Of 229 patients, 74.2% were males. The mean ages of male and female patients were 63.4±12.6 and 64.6±12.01, respectively, indicating no significant difference between the two groups (P=0.534). The majority of samples (78.6%) had non-small-cell-lung cancer and the method of diagnosis was biopsy in 88.9%. The most and least common sites of involvement were the upper edge of the right lung (22.3%) and the upper lobe of the left lung (18.8%), respectively. Among the patients, 85.1% were in stage IV and chemotherapy was the main treatment in most of the patients (57%).
Conclusion: This study showed that men were more infected with lung cancer. We found that the average age of female patients was slightly more than that of male patients. Most of the patients were diagnosed with non-small cell lung carcinoma. The majority of patients were diagnosed at higher stages that were made at advanced and metastatic stages.
Ali Akbari Sari, Ali Mohammad Mosadegh Rad, Ghasem Janbabaee Mola, Seyedeh Elaheh Mousavi,
Volume 28, Issue 162 (7-2018)
Abstract
Background and purpose: Improving patient satisfaction was the main goal of Health Transformation Plan (HTP) in Iran. This research aimed to study cancer patient satisfaction following implementation of HTP in Sari Imam Khomeini Hospital, Iran 2015.
Materials and methods: A descriptive cross-sectional study was conducted in 386 cancer patients using census sampling. Data was collected by administering cancer patient satisfaction questionnaire and analyzed in SPSS.
Results: The respondents reported 70% overall satisfaction. They were more satisfied with the staff attitude and helpfulness, service value, staff competence, and hospital equipment. On the other hand, they were least satisfied with access to recreational facilities, medicines, comprehensive services, pain management and relief, and hospital catering. Patient satisfaction of the HTP was about 64%. About 12, 49.2 and 38.8% of the participants were found to be dissatisfied, moderately, and fully satisfied with HTP, respectively.
Conclusion: Overall, patients were satisfied with The HTP. However, hospital managers should be trained and empowered to apply quality management strategies to increase patient satisfaction.
