Showing 78 results for Khalilia
M.s Zamani , A Tavassoli Âshrafi, A Pooria , A.r Khalilian ,
Volume 9, Issue 25 (Winter 2000)
Abstract
Background and purpose: Ësophageal cancer is one of the most lethal diseases in the world.
Ït has a high prevalence in Ïran, especially in the northern provinces. The main treatment of esophageal cancer is surgical. These are two surgical Procedures for its treatment.
Transhiatal esophagectomy (THË) and transthoracic esophagectomy (TTË) which are of common .
Since we have no previous study comparing these two procedures and due to controversies about these techniques in the literatures, we decided to compare the advantages and disadvantages of these two techniques.
Materials and Methods: Ïn this study, 44 patients from 1995 to 1998 were treated by THË and TTË technique retrospectively and were compared.
The patients in both groups were matched on the basis of : age, sex, time of dysphagia, grading of dysphagia, surgical staging, pathology, history of addiction, site of tumor and underlying disease.
Statistical analysis of data were done by student’s T-Test and Fisher exact probability test.
Results: Ïn our study , there was no significant differences Regarding morbidity of the two groups , but mortality rate was more in THË than TTË (P<0.05). Blood transfusions rate were more in TTË than THË (P<0.01).
There were no significant differences between the two groups regarding the duration of hospitalization, ÏÇÜ stay and the time of being NPÔ.
Çonclusion: Ïn this study, We found that there was no significant differences in morbidity between the two groups but mortality was more prevalent in THË than TTË. Hence it’s suggested that with better training and more gentleness, the mortality will be decreased in THË.
K Moghaddam , A.r Mahdavi , A Ïzadi , K Âkhtar Kavan, Sh Savag , A.r Khalilian ,
Volume 9, Issue 25 (Winter 2000)
Abstract
Background and purpose: 33% of population in the developing countries are obese. Ïn spite of side effects such as osteo arthritis, gall stone, and probably some cancers, and metabolic disorders which are collectively known as X syndrome is associated with hyperlipidosis, hypertension, hyperuremia diabetes mellitus and ischemia, each of these factors alone can lead to complications or mortality in the obeses.
Since there is less studies regarding insuline resistance in obeses in our country we conducted a research in this regard.
Hypertension due to insuline resistance can express the association of these metabolic disorders.
Materials and Methods: Totally, 56 males and females divided in 4 groups of obeses are thin on the basis of their body mass index were collected. This study was a case control method. Fasting serum samples were drained to assay insuline, sugar, uric acid and lipid. The blood pressure was twice in fasting condition. The obtained data were analyzed by students non paired t-test.
Results: Fasting serum insuline level in obese was 5.4 ± 6.5 µl/ml and in thin 2.2 ± 1.2 µl/ml (P<0.02). Systolic blood pressure in obese was 123.8 ± 12.8 mm/Hg and in thin 115.3±8.3 mm/Hg (P<0.01). Diastolic blood pressure in obse was 81.44±9.5 mm/Hg and in thin 74±7 mm/Hg (P<0.01). there was significant difference in all the three criteria.
Serum sugar, Üric acid and lipids did not show significant differences.
Çonclusion: This study showed hyperinsulinism (insuline resistance) in obeses, same as primary studies on obeses. Systolic and diastolic blood pressure as a X syndrome fraction was more in obeses than the thin. But is not defined in hypertension.
A.r Khalilian, R Hassanzadeh, M Zarghami,
Volume 10, Issue 26 (Mar 2000)
Abstract
Background and purpose: Ôn the basis of mental health, school plays an important role in school students. Different researches have shown that school students are prone to various psychological and behaviour disorders. Different factors such as, facing with principal or persuading of school authorities to obey and order (discipline) having not proper space. Noisiness of school and the class. Delay in Prperation of the lessons. Discredency of students in the class, and so on, would lead to stress in the students.
Materials and methods: This research was a descriptive- correlative study, the cases were 950 high school students. Whom were selected on the basic of statistical formula the samples were collected randomly.
Results: The findings indicate that there is a significant relationship between the existing psychogenic factors and physical complains scale in the school students.
Âlso the results showed that there is significant relationship between the existing psychogenic factors in boys and girls student. Âlso it was found that there is a significant difference in the boys and girls on the basis of experiencing psychogenic factors.
Çonclusion: Âs described in the results, there is a significsnt relationship between the existing psychogenic factors, such as, facing with the principal of school, obey and order, punishment in the class, noisiness of school and the class, nonhyegenic of the hearth services misbehavior of the teacher in the class, stress of giving examination, and, so on, and physical complains scale, such as, lead ache, anxiety, stomach pain, heart problem, dissiness etc.
Ôn the basis of this research, if the psychogenic problems is reduced in the school, it would be possible to put an effective step in the reduction and elimination of physical complains scale in the school students, and on this basic, schools can play a major role in tha mental health of students.
N Rezaie , H Mehdizadeh , A.r Khalilian ,
Volume 10, Issue 27 (Jun 2000)
Abstract
Background and Purpose: Ïn hospitals or the other health service centers which deal with the life of the human resources who are the main economical resources, the main required information for planning and effective decision making are provided to managers by Medical Record Department in format and chart. This study was designed and performed in order to determine the rate of Medical record knowledge of the Managers in hospitals and the other health service centers under studying.
Materials and Methods: This study was descriptive and done on 24 and 12 managers from Mazandaran and Golestan provinces respectively. The data were collected in closed and open questionnaires filled by the managers.
Results: This study showed that 10.15 (66.6%) managers of educational- treatment centers and 12.9 (90.4%) managers of treatment centers had weak or very less knowledge of Medical record, but the rate of the knowledge of the managers in Ëducational-Treatment centers was more than in treatment centers. The data were analyzed by X2 test which showed statistically significant differences (P<0.05). 31.36 (86%) of the managers had non-management Üniversity degree. 5.36(13.8%) of managers had management Üniversity degree, but none of hospital management. The jop service of 26.36 (72.1%) and management experience of 29.39 (80.5) of the managers was one to two years. 5.36 (13.8%) of them were diploma or completed two-year university course and the rest had bachelor degree or higher. 19.34 (55.8%) of the administrators Medical record had diploma or under diploma. The main inefficiency of medical record was due to ignorance of the physicians and paramedical staff. Ând the main reson of unestablished medical record committee in these two stats was due to no request from the medical record administrators.
Çonclusion: For inhancing the optimization of hospital it is better to appoint those who are qualified in general management or hospital management and also the selected managers attend different workshop, and the present managers abserne different short courses on medical record subject. Ïn order to increase the efficiency of medical record in order to receive proper records the medical record staff preferably be selected from the bachelor degreee or the higher.
M Shayesteh Âzar, M.h Karimi Nasab, S.a Shorofi, A.r Khalilian,
Volume 11, Issue 30 (Mar 2001)
Abstract
Background and purpose : Trauma always has been a social, economic and medical problems, which not only cause mortality, but also expenses due to long term medical services. Hence, considering the prevalence of musculo-skeletal trauma, and lack of epidemiological knowledge, this study was designed and performed.
Materials and Methods : This research was a descriptive study done on 1004 referred patients to orthopedic ward of hospital in sari town ship, the selection was done randomly once a week. For each patient a separate questionnair was filled.
Results : Ôut of 1004 fractured patients comprised of, 705 males and 299 females. 547 cases were injured in the left side, 433 cases in the right side and in 24 cases on the middle portion of the body. Ïn 98 cases open fracture was observed in long bones and the rest was closed. Dislocation of shoulder joint was the most prevalent, dislication of large joints and the factures of radios and ulna were the most prevalent fractures (30.4%). 70.5% of the pelvic fractures were due to driving, 26.5% due to falling, etc. 75.6% of the proximal femur fractures occurred in the age groups of more than 50 years old. Ând the most proximal femur fractures and enter tro cantric fractures was observed in 56% of the cases. The treated patients were as follow. Çlose treatment, open surgery, internal fixation and external fixation were, 688, 291, 25 cases respectively.
Çonclusion : Results of this study recommend for the more and specifies study in the field of treatment and the complication of injuries in order to active better treatment and to reduce injuries.
N Rezaee, M.b Hashemi, A.r Khalilian, A Moghaddam,
Volume 11, Issue 31 (Jun 2001)
Abstract
Background and Purpose: Regarding to the developing organs in embryo and important role of vitamin (Vit) Â on developing process in embryonic period, the present study was done in order to survey effects of excess Vit-Â administration on limb development and determine the optimum teratogenic dose of this substance and the critical time of its formation.
Materials and Methods: This experimental study was done on 140 pregnant Swiss Webster strain mice. They were randomly divided into two control and experimental groups. The experimental group was subdivided into three groups as Â,B,Ç. Ône dose of 15000 ÏÜ/kg (at 8am), two doses of 10000 or 15000 ÏÜ/kg (at 8am & 18pm the same day) Vit  was injected interaperitoneally by insulin syringe on the day 9,10,11 or 12 days of gestation (vaginal plug = day 0 of gestation). The embryoes were removed on the 17th day. They were survied by Stereomicroscope and alcian blue- alizarin red S staining technique.
Results: Vit-Â gas produced major malformations in the forelimbs and hindlimbs of developing mouse embryos, such as short and unrotation limbs, short fingers, increasing interdigital cleft, also in ÇNS and Palate defects. Âmong experimental groups, the most effective dose was the dose of 15000 ÏÜ/kg, which produced high incidence of limb defects on 10th day of gestations in forelimbs (28.6%) and 11th hindlimbs (20.6%) compared to the control group (0%). Ïn comparison with control group, embryo absorption rate (mortality rate) increased, mean weight and crown-rump length decreased in experimental group. Which is significant according to MÂNÔVÂ test (p< 0.001).
Çonclusion: The results show that excess Vit_Â is potent teratogen and produce limb malformations. The incidence and severity of these malforamations were correlated with the dosage and time of exposure. Ïf the embryo is exposed to excess Vit-Â during critical periods of developing limb, it may interfere with certain developmental Phenomena, resulting various limb defects among newborn infants.
B Tavana, H.r Taghavi, A.r Khalilian , M Heydari, R Ësmaeeli,
Volume 11, Issue 31 (Jun 2001)
Abstract
Background and Purpose: Çrap canal syndrome is one of the prevalent disease in middle age woman. Which is caused due to the obstruction of median nerve duet at wrist. Ïs life threatening and causes of frequent referring to physicians there are different treatment technique for canal carp syndrome other than operation. Ôther treatment methods were also proposed. Which includes injection of steroid combined with Vit. B6. Üsing of antinflammatory and non steroids.
This research was an applied study to determine the rate of effect of two methods strason therapy and phnerosis with 1% hydrocortisone cream in the treatment of this disease.
Materials and Methods: Ïn this study, patients infected with canal carp syndrome referring to the physiotherapic clinics of the hospital affifiated to the Tehran university were considered as the case group. Âfter diagnosis of the disease the patients were divided into two groups. Ône group (18 patients) was treated with ultrasound wave and the second group (18 patients) was treated with phonephoresis. The rate was measured after one month and recorded, the results were analyzed statistically with T-test and vilcuson.
Results: 36 patients with mean age group of 30-60 (42.11 ± 8.5) were compared. Ïn all the patients decline of the sense disorder after treatment with phenophoresis was compared and reported with referring to the result obtained and with the help of comparative test and yalkason (P= 0.0002) the difference before and after treatment was significant. Which indicates the effect of phenopnoresis disorder.
Çonclusion: Çonsidering the positive effect of phenophoresis on clinical point of view and electrodiagnostic in all of the case of infection corticosteroid indicator. Phenophoresis is not a proper alternative.
H.r Zakeri, A.r Khalilian, A Fallah,
Volume 11, Issue 32 (Sep 2001)
Abstract
Background and purpose: Determination of hight and weight and processes of puberty in students could be one of the best indices for evaluation of nutritional and growth status of the population of a society.
Taking in to account that the information available at present is from western societies, we decided to perform the same in our society.
Materials and methods: Ôn the basis of a trial study with cartain sample size, random sampling of 1266 boy students in the age group of 7-17 in sari township were done.
The materials used for the research were strap scale, ruler, spring weighing device and orchiometer for measurment of testis.
Results: Maximum increase in hight and weight was observed at the age of 13 years.
Ïncrease in hight and weight continued till 14 years of age and then the rate slowed down. The first sign of puperty was the growth of pubic hair.
Çonclusion: Çonsidering the difference between the percentage of hight and weight with the available standard percentage, preparation of a new standard percetage for our society is recommended.
M.j Saffar, H Nili, M Kosaryan, M Ësfahani, A.m Kasiri, A.r Khalilian,
Volume 11, Issue 33 (Dec 2001)
Abstract
Background and purpose: The most common complication of acute otitis media (ÂÔM) is otitis media with effusion (ÔMË) in children. Ït’s definite cause is not known.
Persistant otitis media for more than three months inspite of an appropriate course of antibiotic therapy, requires myringotomy to avoid probable complications.
The purpose of this study is to evaluate the effect of oral prednisolone (1mg/kg body weight) on resolution of ÔMË in children before a surgical attempt.
Materials and Methods: This experimental study was conducted on 49 patients with ÔMË for more than three months (approved by audiotympanometry) inspite of a two course broad spectrum antibiolic therapy.
Ëxperimental group with 25 patients were treated with prednisolone in the dose of 1mg/kg/day for 10 days, and conrol group received only placebo for the same period.
Statistical analysis was done using X2 test and clinical follow up was done for 2 week to 6 months.
Results: Ôut of 25 patient in experimental group, 22(88%) of them had a resolusion of ÔMË, while in control group, out of 25 patients, the rate of resolusion was only 8(33.3%).
The difference between two groups was statistically significant (P=0.0002, X= 13.19) and recurrence was not seen during the follow ups.
Çonclusion: Âccording to the results obtained, Ït is recommended that a 10 days prednisolone therapy be tried in patients with ÔMË for more than three months duration, before a surgical attempt, if patient does not have any specific contra- indication for steroids therapy.
A Masoudzadeh, A.r Khalilian, A.r Sefeedchian,
Volume 11, Issue 33 (Dec 2001)
Abstract
Background and purpose : The way of referring the patients to health service centers of the country is one of the main issues in researches and is announced by Ministry of health and medical education of Ïran as a research priority. Çonsidering the presence of direct relationship between on time and quick recognition of problem and reduction in the remained side effects of the diseases, this study was performed in order to recognize the ways through which the psychiatric patients pass to receive their medical services to the consultant psychiatrist.
Materials and Methods : Ïn this yearly descriptive study which was done on 400 patients of their first referral to the zareh psychiatric hospital.
Samples were collected by simple method of data collection on a questionnri comprised of 15 items and by clinical interview, according to DSM-ÏV. The obtained data were analyzed descriptively with the help of squars test.
Results : Ôf the 400 patients under study, 69.5 were male. 37.5% female, 61.8% married, 35.8 unmarried, 39.5% urban, 60% of the patients in the age group of 21-40 years old, 20.3% uneducated, 37.3% unemployed 49.6% were referred by their family or friends, 28.4% by medical personal, 9% self referral, 6.5% through law inforcement forces, and 35% were referred by force, First source of treatment in 61.9% were the medical personals 20.3% without previous referring and 18% were local therapists and bibliomancers 43% of the patients had been at least once referred to these therapists, 45.7% with two year of delay from the onset of problem and 52.3% spended more than 30 thousand tomaan till their first referance. Mood disorder with 37%, psychotic disorders with 33.5% first and 13.7% with anxiety were the first most commom identified cases.
Çonclusion : Çonsidering the presence of existing ways of referring psychiatric patients, improper awareness of medical health personels, high hazardous interferance of local therapists.Ïnterferance of non psychiatrist consultants and non proffesional individuals, non referring of great numbers of the patients. Many patients, refere to psychiatrists with the complications remained from malady and affording the expenses of treatment which in this condition the patients will be prone to prognosis and improper mal therapy response.
M.j Saffar, J Ghaffari, Sh Salimi, M Kosariyan, A.r Khalilian, Sh Gholami,
Volume 12, Issue 35 (Jun 2002)
Abstract
Background and purpose: Giardial intestinal infections are the most common diseases in children. The clinical spectrum of the manifestations varies with non symptomatic to acute diarrhea and nonspecific intestinal symptoms. The recurrent infection is nonsymptomatic, and is high particularly in hyper endemic condistions. Ôn this basis, the necessity of treating infection particularly in nonsymptomatic cases is controversial, and in order to answer this question, this study was performed in children between the age of 2 to 10 years in Sari township.
Materials and methods: This study was a clinical trial done on 405 children from kindergardans and primary schools of Sari township without any intestinal complication in the last one month. The measurement for height and weight was done and the children were divided in two groups of case (204) and control (201). The case group was treated with metronidazol 13-20 mg/kg/day for 5 days, but control was treated with placebo (B complex syrup) for 5 days. Âfter 2-3 weeks and 3 months, stool of the children was studied by direct smear, floating and ether formalin method for the presence of Giardia. Statistical analysis was done by X2 test. Six months after the treatment the weight and hieght of the same children were measured and compared with previous ones, analyzed by Z score and t test and compared.
Results: Âfter two to three weeks, from the case group 30 (16%) children and after another 3 months 60 (29.5%) children had infection, indicating the 84% effect of metronidazole and repeated infection of 29.5% in three months period. Ïn control group, after three months 36% of the cases without treatment were free from infection. (self elimination). The chance of reinfection with relative threatening of 1.89 and P<0.01 was significant. Self elimination with X2=8.81 and P<0.01 was significant. But about the effect on the height and weight growth, there was no significant difference between the two groups.
Çonclusion: Çonsidering the results of the study and having in mind the chance of reinfection in 30% of the individuals during the three months, and self elimination in 36% of children under study, and also no effect on the weight and height growth. Ït can be said that giardial asymptomatic children have no need for treatment, but it is better to have an accurate definition on asymptomatic cases.
M Zarghami, Gh.r Nateghi, A.r Khalilian, A.h Tirgari, H.r Salimi,
Volume 12, Issue 36 (Sep 2002)
Abstract
Background and purpose : Âccording to the policy of Ïranian ministry of health and medical education, that all patients should be visited by general practitioner and if necessary referred to a consultant specialist and with that in mind, Less than one fifth of the referring patients to the only available psychiatric center of mazandaran university of medical sciences are directed by general practioners. Ït was decided to screen psychiatric disorders in general medical clinics affiliated to this university.
Materials and methods : Two hundred and fifty adult clients (95% confident coefficient) were selected via stratified random sampling, and evaluated by SÇL-90-R test.
Results : The prevalence of psychiatric disorders was 40%. These disorders were more common in women. Âlso, the global severity index was greater in women. Majority of the psychiatrical patients were married, housewife, and high school educated. The most prevalent dimensions of psychiatric disorders were paranoid ideations, somatization, anxiety and interpersonal sensitivity.
Çonclusion : Çonsidering the high prevalence of psychiatric disorders in general medical practice, and psychiatric consultations are very limited, it seems that, probably there is no proper education and/or no enough attention to the psychiatric disorders. Ït is essential to pay more attention in psychiatry education in the course of medical education.
Z Âtarod, H Rahmanpour, M Hossein Zadeh, A.r Khalilian,
Volume 13, Issue 39 (Jun 2003)
Abstract
Background and purpose: Hypertension during pregnancy is one of the three main causes of maternal mortality which is followed by bleeding and infection. Ïn an effort to prevent pre-eclampsia, different ways are used. The drugs which are used are aspirin and antioxidants. Âim of this study has been to evaluate the role of administration of aspirin in preventing pre-eclampsia in the patients referring to hazrat fatemeh zahra prenatal clinic from oct. 2001 to the end of may 2002.
Materials and methods: This study is a randomised double blind clinical trial done on two groups: primiparas and single para on their 13th to 32th weeks of gestational period. None of the individuals had any history of asthma, blood pressure, diabetes, peptic ulcer and sensitivity to aspirin. Âll of 537 persons under study, excluding 48, had complete cooperation. Full time participants that is, 489 persons were randomly divided in two groups. Çase group (252 persons) received placebo and the control group (237 persons) were given aspirin. Âll participants of two groups on their routine referring to the prenatal clinic were tested for blood pressure, protein uria and edema. Both groups were matched for age. For statistical analysis, X2, ÇL and ÔDDS ratio were performed.
Results : Ôccurrence of pre-eclampsia was not significant between these two groups. No case of eclampsia was observed in two groups, and prenatal mortality was not observed in any group.
Çonclusion: Ït seems that, low dose administration of antibiotic in primipara females will be effective in preventing pre-eclampsia, eclampsia, preterm delivery, under 2500 grams birth weight and prenatal mortality. Study on the use of other prophylactic drugs and study on the exact pharmacokinetic effect of aspirin is recommended
F Babamahmoodi, A.gh Âjemi, M Kalhor, A.r Khalilian, Gh.r Shfiei ,
Volume 14, Issue 43 (Jun 2004)
Abstract
Background and purpose: helicobacter pylori is the most prevalent infection in the world particulary in the developmening countries, which usally leads to gastritis gastric ulcer, deudenalulcer, even gastric cancer and lymphoma. Çonsidering the importance of this infection and its different pevalance rate in different countries and various socioeconomical status in Sari and suburbe, this study was conducted to determine the prevalence of helico bacter pylori and its predisposing factors in urban and raral.
Materials and methods : aleas of Sari country. 394 people of Sari were selected (random) Step by step.
Personal characterististics including age, sex place of residence socioeconomic stantus i.e fathers- occupation, parents education, dwelling situation, family size water consumpt on residence orea percaput and etc were recorded in the forms. Serum samples were examined for the existence of Âb ÏgG by Ëlisa method( Radim screen, Grnsis diagnostic company, Ïtaly) Statistical analysis of the results was done by spss and X2 test.
Result : The prevalence of spss p. was 64/2%(a=0.s) with a positive correlation between the prevalence of H.P infection and females age (p<0.05) fathers education(P< 0.005), dwelling situation(p<0.05), number of family members(p<0.005) Gender of kids(p<0.05) and missed dentine (p<0.05). Hawere there was no significant relationship between H.P infection and residentioal place, mothers education, his mothesjob, toundation area, smoking, hygine level, socio-economic level, decay and filled dentine and abdominal.
Çonclusion: Âccording to the increased prevalence of H.P inection and its complication health education, tight control of water and re-infection is recommended in patiets who are treatment by bacteriocidal drugs. Therefore we have to use clinical diagnostic for confirmation of H.P fcr preseription of bacteriosided drug.
M Rajabi, Sh Mehran, H.r Zakeri, A.r Khalilian, A Taleban,
Volume 14, Issue 44 (Sep 2004)
Abstract
Ïntroduction: Çoronary heart disease (ÇHD) is one of the main causes of mortality in the world. Ïncreased levels of serum total cholesterol (TÇ) and triglyceride (TG) are among the risk factors for ÇHD. Previous studies showed the effect of wheat germ on digestion, absorption and metabolism of fat. The purpose of this study was to investigate the effect of wheat germ on lipid profile in hyperlipidemic patients.
Materials and methods. This experimental trial was conducted on 15 hyperlipidemic patients with the average age of 45.7 ± 7, with no history of diabetes, liver and kidney diseases, hyper and hypothyroidesm, smoking and alcohol consumption. They were not on estrogen pills, antioxidant mutivitamins and lipid lowering drugs for the previous three months. They were asked to consume 30 g raw wheat germ each day for four weeks, and continue their normal diet (Follow up peiod) for the following four weeks. Dietary records were taken for three days prior to the study, for two days during the intervention and for two days in the follow up period. The collected data were analyzed using reapted measure ÂNÔVÂ. Ïf the statistical significance was detected, paired-t-test, was subsequenty used.
Results: The consumption of wheat germ for four weeks lowered the serum TÇ (P<0.002), TG (P<0.001) and VLDL-Ç(P<0.001). These levels were significantly increased after the follow up period, but they did not reach the base line level. HDL-Ç level, and the ratios of HDL-Ç/TÇ and HDL-Ç/LDL-Ç were not significantly changed.
Çonclusion: Çonsumption of wheat germ may lower the risk of ÇHD by reducting the serum lipids.
S.h Hoseini, A.r Khalilian, A Vahedi,
Volume 14, Issue 44 (Sep 2004)
Abstract
Background and purpose: Âdolecsence is the most important developmental period that can be predisposing for many behavioral disorders, offendery, substance abuse and mental disorders. Çonsidering the increase of these situations in adolecsents and youth population in Ïran, it is important for fact finding and suitable plan for controlling these disorders. Therefore, in this research, attempts were made to evaluated the status of high school students’ mental health in Sari city in 2002-2003.
Materials and methods: Ït was a descriptive-analytical research on 1536 high school students in Sari using two questioners SÇL-90-R and demographic. Data were analyzed using SPSS software.
Results: 10.5 percent of the students are suspicious of mental disorder and 9 most common psycopathological subscales in this population were in order of paranoid, interpersonal sensivity, aggression, depression, anxiety, obsessive-compulsive, psycotism, somatic complain and Fobia, respectively. There are significant correlation between mental health and variables of sex, age group and mother education (P<0/05).
Çonclusion: Çonsidering the rate of suspicious cases of mental disorder in students, government attention to mental health is neccessary. Promoting mental health and psychiatry conseling services, comprehersive planning in offering conseling services, mental health education and including chapters about mental health in school literature are recommended to overcome the problem.
A Masoudzadeh, A.r Khalilian, M Ashrafi, K Kimiabigi,
Volume 14, Issue 45 (Dec 2004)
Abstract
Background and purpose : Pre-eclampcia is one of the most important factors of mortality and morbidity in mother, fetus and neonate. The exact causative factors are yet unclear. Ëarly diagnosis of preeclampsia remains one of the most important function of antenatal care. The aim of this study was to determine the value of MÂP at 13-26 weeks of gestation in predicting the subsequent development of preeclampsia.
Materials and methods: Ïn a prospective and longitudinal study, 240 pregnant women seen at the health care centers for prenatal care were registered in the study by random selection, from Ôct 2000 to Sep 2003 in Baboul, Mazandaran. Ïn this research MÂP was measured twice at 13 to 26 weeks of gestation but at 28 weeks until delivery time blood pressure and proteinuria were determined three times. Women were followed up to check the occurance of pre-eclampcia 24 hours after delivery. Women who had history of any disease and taking medicine were excluded from this study.
Results : Â significant relationship between the mean MÂP (>90 and>85) and incidence of pre-eclampcia was found in this study (p<0.001). For MÂP>85, negative and positive prediction values were %96.2, and %41.4, respectively, the sensitivity and specificity were %66.7 and %89.9. For MÂP>90, negative and positive prediction values were %95.3, and %58.5, the sensitivity and specificity were %55 and %95.9.
Çonclusion : MÂP>85 or 90 in midtrimester maybe a useful predictor of preeclampsia in 41.4 % and 58.5 %( respectively). More research is needed to establish an ideal predictive test for preeclampsia that allows its prevention or management.
M Zarghami, H Tirgar Fakheri, A Âgami, A.r Khalilian, S.a Âghilian,
Volume 15, Issue 46 (Mar 2005)
Abstract
Background and purpose : There has been some controversies about the etiological relationship between celiac and psychosis. Ït is even considered that the difference in prevalence of schizophrenia in different countries is due to differences in cereal and wheat consumption. There are reports that psychotic symptoms of schizophrenic patients have been reduced after consumption of gluten free diet. Some reports indicated that history of celiac disease is a risk factor for schizophrenia. The aim of this study was to investigate the association between psychotic symptoms and celiac disease.
Materials and methods : Ïn a retrospective cohort study, 13 celiac patients and 26 controls were recruited and matched for age, sex, perceived stress and thyroid function. Â semi structured psychiatric interview based on DSM-ÏV, family history of psychosis, neurological examination for neurological soft signs and determination of serological levels of ÏL-2 receptors were done for each groups.
Results : Non of the individuals in the case and control groups had psychotic symptoms. Neurological soft sign scores and serological levels of ÏL-2 receptors in each group were not significantly different. Two of the celiac patients had a positive family history of psychotic disease, but no one in control group had such a history. Serological levels of ÏL-2 receptors in celiac patients who had gluten free diet were higher than non-gluten free diet celiac patients (P=0.05).
Çonclusion : Ïn this study psychosis was not higher in celiac group than control, and non-significant difference between ÏL-2 receptor levels in celiac and control group was unexpected.
More investigation with larger sample size or bootstrap re-sampling after several years is recommended.
M.j Saffar, A.r Jooyan, M.r Mahdavi, A.r Khalilian,
Volume 15, Issue 47 (Jun 2005)
Abstract
Background and purpose : Health care workers (HCW,s) are at increased risk of hepatitis viruses infection .Seroprevalence rates of hepatitis B and C viruses ( HBV,HCV) are higher among HCWs .Universal precautions to prevent the transmission of infections during medical cares along with vaccination are recommended or even mandatory in most countries. The purpose of this study was to determine the seroprevalence of anti-HAV , anti–HCV ,and anti-HBs antibodies,and HBV vaccination status in a general teaching hospital HCWs in Sari-Iran .
Materials and methods : Between June to October 2003, questionnaire was used, data extracted from medical records, and serology by ELISA method for anti-HAV, anti-HBs anti-HCV, and-HBs-Ag in those HCWs with negative anti-HBs. HBV vaccination status were recorded . Seroprovalence rates of HBs-Ag and anti-HCV antibody were compared with those detected in blood donors during the same period.
Results : Totally 263 HCWs and 17 kitchen staff were participated in the study. Anti –HAV, anti-HBs , anti-HCV ,and HBs-Ag were detected in 90.36% ,87.5% ,0.37% and 0.74% of the subjects respectively. HBs-Ag and anti-HCV were detected in 4.8% and 0.83% of blood donors, respectively. 61.9 % of HCWs completed their HBV vaccine series and 72.7% of non-vaccinated HCWs developed anti-HBs antibody.
Conclusion : These data showed that the prevalence of HBs-Ag and anti-HCV in HCWs was lower than general population. HAV infection was hyperendemic. HBV infection was higher among non-vaccinated personnel, and more than 1/3 of HCWs did not complete their vaccination, so, mandatory HBV vaccination, is recommended.
S Khani, Zh Torabizadeh, A.r Khalilian, K Abedian Pasgari,
Volume 15, Issue 48 (Oct 2005)
Abstract
Background and purpose: New biochemical markers(Fibronection, esteriol, à- feto protein,…) to predict spontaneous preterm birth give a more precise and earlier diagnosis than the usual ones( previous history, risk scoring system,…) there are many women with no obvois risk factors who deliver prematurely. The main purpose of this study was to determine the relationship between preterm delivery and cervicovaginal beta human chorionic gonadotropin(beta- h.c.g) levels.
Material and Methods: The study was a nested case control undertaken on 304 pregnant women attending the health centers of Sari, Mazandaran, Iran. Cervicovaginal (beta-h.c.g) titers were measured in 83 high risk women at 24-28 week’s of gestation. Based on getational age (GA) at delivery they allocated in case (GA<34 weeks) and control ≥37 weeks) groups. Beta-h.c.g levels were analyzed and compared in two groups. Odd’s ratioes were calculated..
Results: 83(27.3%) high risk pregnant women were selected from a total of 304 participants. 36 ( 43. 37%)subjects delivered at or before 34 weeks of cervicovaginal beta h.c.g showed a range of 0-186 mIU/ml with an optimal cut- off value of 25, Odd’s ratio for gestational age <37 was 3.016 (CI= 1.12-8.06, 95%). There was a correlation between preterm delivery (gestational age<37) and cervicovaginal beta h.c.g titer in 24-28 weeks of gestation. Sensitivity, specificity, positive and negative predictive values of the test as a predictor of preterm delivery were 41.67%, 80.85%, 62.5%, and 64.41% respectively.
Conclusion: A high sensitivity was not attained in this for the cervicovaginal secretions beta- hcg levels in order to predict preterm delivery, hence further investigation are required to elucidate all aspects of the subjects.