Showing 3 results for Tarashi
A Daryani, M Sharif, B Laktarashi, Sh Gholami, H Ziaei, A Ajami, A.r Rafiee, A.m Mirabi, R.a Mohammadpour,
Volume 16, Issue 54 (Oct 2006)
Abstract
Background and purpose: Toxoplasmosis is a widespread zoonosis caused by Toxoplasma gondii. In addition to economic losses, this disease is transfer able to human and regarding the special ecological conditions of this parasite in nature of Mazandaran province, it is necessary to determine the situation of the disease. The purpose of this study was to determine the frequency of antibodies against T. gondii in cattle, sheep and goats slaughtered in official slaughterhouses in Mazandaran province, in 2004.
Materials and Methods: To determine the prevalence of toxoplasmosis in slaughtered animals, in a descriptive cross-sectional study, 639 blood samples were obtained from cattle, sheep and goats between December 2004 and April 2005, from the three main geographical zones of Mazandaran province, Iran. Nine slaughterhouses were randomly selected in Western, Central and Eastern regions. Sera were extracted from 5mL venous blood samples, by centrifugation at 2000xg for 10 min, and were stored at –20º C prior to testing. Sera were screened for T. gondii antibodies by immunofluorescence antibody test (IFAT) and serum samples showing a titre of 1:16 were further diluted to determine the end point. Data were analyzed using Chi-square (X2) test.
Results: Of the 639 serum samples examined, 27.5% (176/639) showed positive titers equal or higher than 1:16 by IFAT. The highest frequency of antibody titres (1:16 titre) were found in sheep and the least in cattle (9%). The highest infection rates in cattle were seen in western region with 5.5 % antibody titres of 1:16. In three regions, 35% of sheep sera showed positive titers with high frequency of 1:16 antibody titre (17.3%) in Western region. Thirty percent of goat sera in 3 regions were seropositive and the highest infection rate was seen in 1:16 titre (18.5%) in Western region.
Conclusion: The results of this study show that the presence of T. gondii specific antibodies for sheep and goats in Northern Iran is high, and the consequent risk of acquiring toxoplasmosis from human consumption of sheep and goat meat may be greater in this region.
Mehrzad Sadredinamin, Ali Hashemi, Hossein Goudarzi, Samira Tarashi, Neda Yousefi Nojookambari, Elahe Taki,
Volume 26, Issue 138 (June 2016)
Abstract
Background and purpose: The prevalence of antibiotic resistant P. aeruginosa strains became a major problem in treatment of burn patients. The aim of this study was to determine the frequency of blaIMP, blaVIM and oprD genes among P. aeruginosa isolated from hospitalized burn patients in Tehran Shahid Motahari Hospital, Iran.
Materials and methods: This descriptive study was performed on P. aeruginosa strains isolated from hospitalized burn patients in Shahid Motahari Hospital. Antibiotic resistance phenotypic pattern was evaluated by Kirby Bauer disk diffusion method. The phenotypic investigation of metallo-beta-lactamase (MBL) producers was evaluated by Combined Diffusion Tests Disk (CDDT) method. The prevalence of blaIMP-1, blaVIM-1 and oprD genes was investigated by PCR and sequencing methods.
Results: From 100 P. aeruginosa strains, 95 isolates were resistant to imipenem and meropenem which 81 were MBL producing strains. Among all isolates, 13 carried blaIMP-1 gene, whereas all of strains were negative for blaVIM-1 gene. In this study we detected two insertion sequence (IS) including ISPpu21 and ISPa1328 among PCR products that were larger than expected.
Conclusion: The P. aeruginosa infections could be prevented and controlled by identification of drug resistance patterns and beta-lactamases.
Samira Tarashi, Mir Davood Omrani, Arfa Moshiri, Seyed Davar Siadat,
Volume 30, Issue 193 (1-2021)
Abstract
Some organisms may modulate a healthy state or cause disorders by disruption or induction of several signaling pathways in human body. According to recent evaluations, numerous metabolic disorders such as diabetes, obesity, cardiovascular diseases, mental disorders, and cancers are as the result of bacterial interactions with the host. Various species of the bacteria, called commensal microbiota, live in normal human body which modulate some of the host critical functions by different mechanisms. Induction of epigenetic modifications in host cells that are important in the maintenance of homeostasis or induction of disorders is amongst these mechanisms. Indeed, different factors may induce epigenetic modifications. For example, diet and its effect on microbiota community may epigenetically change the expression of some specific genes. Such modifications may also be dangerous and inherited to next generations. The current review tried to explain the inter-talk between gut microbiota and epigenetic modifications in health and disorders.
