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Mohammad Azadbakht , Seyede Mobina Mirjani, Majid Yousofi, Mina Amini,
Volume 24, Issue 122 (3-2015)
Abstract

Background and purpose: Drug supply system is one of the most important parts of every healthcare system. Logical prescription and rational use of drugs are important factors that guarantee health in the society. According to official reports, every Iranian consumes 442 drugs per year, amongst which a considerable number is not prescribed by physicians. Emergence of microbial resistances, adverse drug reactions and increasing burden of unnecessary health care spending are due to irrational use of drugs. This study aimed at investigating the consumption and prescription of drugs in Mazandaran Province in inpatient and outpatient settings. Materials and methods: In an experimental study, 23 governmental hospitals and 11 private and Social Security hospitals were chosen by Health Information System (HIS). Then a list of top-selling drugs (2013-2014) and their prices in outpatient settings was obtained. The information of outpatient settings was also collected by Noskhe Pardaz software. Data was then analyzed and compared with the reports provided by Medscape. Results: In the top-selling list of the inpatient settings, there were twenty drugs (all in injection form), of which, seven were antibiotics. Also, expensive drugs such as Albumin, Vial Pantoprazole and IVIG were amongst the nine highly consumed drugs. In outpatient settings, injectable form of Dexamethasone was found prescribed more than other drugs in Mazandaran. Conclusion: High numbers of antibiotics and injectable drugs used for inpatients and outpatients in Mazandaran province calls for more focused attention on consumption and prescription of drugs
Fatemeh Izadpanah, Mina Amini, Atefeh Asadollahpour, Zeinab Esfahani, Majid Yousofi,
Volume 30, Issue 185 (5-2020)
Abstract

Background and purpose: Adverse drug reaction (ADR) is one of the major causes of mortality and morbidity in patients that results in high healthcare costs. This study was conducted in Food and Drug Deputy at Mazandaran University to evaluate ADRs in Mazandaran province.
Materials and methods: The analysis was performed during 2004-2018, based on the frequency of the drugs that had side effects, routes of administration, the number of reports per year, patient characteristics (gender, age), the frequency of the organ damaged, and the reporter.
Results: A total of 4425 reports of ADRs were submitted to Adverse Drug Reactions Center in Food and Drug Department, Mazandaran province, Iran. More than half of the reports (61%) were reported by nurses and 58.4% of the ADRs occurred in women. Injectable drugs were found with more adverse effects (75.7%) and the most prevalent were skin and hair disorders (50.6%). Anti-infective agents were the top drugs that caused ADRs (52.2%) and ceftriaxone was the most prevalent.
Conclusion: Due to the low number of ADRs in Mazandaran province and its low concordance with international standards, it seems that trainings based on the needs and preferences of medical groups about pharmacovigilance and focuses on how to report, can increase their awareness and knowledge about ADR and bring the data closer to world standards.

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