Showing 3 results for Osteomyelitis
Amirhossein Pakravan, Pooya Jannati, Mehran Mansouri, Tahmineh Bamdadian, Milad Karamloo,
Volume 26, Issue 138 (7-2016)
Abstract
Histiocytosis is a term applied to a group of rare disorders of the reticuloendothelial system. Eosinophilic granuloma is the most benign and localized of the three Langerhans cell histiocytosis (LCH) entities that could be solitary or multiple. In 2015, the incidence of the disease was reported to be 1 in 9100000. Eosinophilic granuloma can affect almost any bone, but commonly involves the mandible when the jaws are affected. Conventional treatment of LCH includes surgery, radiotherapy, chemotherapy and steroid injections (alone or in combination). Spontaneous regression of localized disease has also been reported. We report a 30-year-old man with the LCH solitary eosinophilic granuloma in the mandible. The patient had lost all the mandibular teeth because of a misdiagnosis with periodontitis and osteomyelitis.
Nafiseh Jirofti, Azadeh Shahroodi, Jebreil Movaffagh, Bibi Sedigheh Fazly Bazzaz, Rezvan Yazdian-Robati, Maryam Hashemi,
Volume 33, Issue 220 (5-2023)
Abstract
Background and purpose: Topical antibiotic medication is an alternative method in treatment of local infections, especially osteomyelitis. Currently several biomaterials are used for this purpose. The present study focused on the fabrication and characterization of chitosan and Vancomycin (VCM)-loaded chitosan (CS)-hydroxyapatite (HA)-gelatin (G) bead in treatment of osteomyelitis.
Materials and methods: CS/G/HA/VCM scaffold was prepared by cross-linking using ionotropic gelling. The morphological and mechanical properties, loading efficiency and antibacterial properties were investigated and toxicity assay of fabricated structure was also analyzed.
Results: The lyophilization reduced the area, environment, and sphericity of beads. CS/G/HA/VCM structure showed smaller area (4.5 mm2) and perimeter (180 µm) compared to other structures. Suitable morphology and porosity in fabricated beads were confirmed by SEM images in CS/G/HA and CS/G structures. Reduction of strength was observed after adding VCM into fabricated structure, but this happened less in CS/G/HA/VCM structure. Release on day 14 was 58% for CS/G/HA/VCM structure. AddingVCM into CS/VCM (1.88 Mpa) and CS/G/VCM (10.46 Mpa) structures decreased the mechanical strength while it increased the mechanical strength in CS/G/HA/VCM (83.21 Mpa) structure. No toxic activity of fabricated structures was seen against NIH 3T3 cells. The results of the antimicrobial activity against Staphylococcus aureus showed that chitosan beads containing VCM (CS/VCM, CS/G/VCM, CS/G/HA/VCM) could significantly inhibit the growth of S. aureus compared to the positive control (VCM 5%)(P<0.001).
onclusion: According to current study, the CS/G/HA/VCM structure can be introduced as a promising candidate in treatment of osteomyelitis.
Mona Alimohammadi, Hoora Hadian, Jaber Mousavi, Mehdi Aryana, Seyed Rasul Tabatabaei,
Volume 33, Issue 223 (8-2023)
Abstract
Background and purpose: Condensing osteitis is the local reaction of bone to a pulp inflammatory stimulus with low intensity and long duration and is the most common radiopaque pathogen lesion in the jaw. The aim of the present study was to evaluate the frequency of condensing osteitis in apex of teeth with deep caries and restorations in panoramic radiographs.
Materials and methods: This cross-sectional study evaluated panoramic radiographs of 2039 patients attending Sari Dental School clinic for dental treatments during 2018-19. Demographic information, including age and sex were recorded. All panoramic radiographs were taken with Cranex D (soredex, Finland) panoramic device and Ortho CP-G Plus films. Lesions in the area of teeth with extensive restoration or deep caries (condensing osteitis) were examined in both jaws. Data were analyzed in SPSS V21 using Kolmogorov-Smirnov test, Fisher's exact test and Chi-square.
Results: According to findings, 364 panoramic radiographs had condensing osteitis. The frequency of radiopacity at the apex of teeth with condensing osteitis was significantly higher in women than men (P=0.042). But there was no significant association between condensing osteitis and border, shape, jaw type, tooth type, and age (P<0.05).
Conclusion: This study showed a relatively high prevalence of condensing osteitis in our patients in dental clinic at Mazandaran University of Medical Sciences. Current findings support the theory that condensing osteitis lesions may form a reaction associated with severely decayed, restored, or pulpitized teeth.
