Volume 30, Issue 188 (9-2020)                   J Mazandaran Univ Med Sci 2020, 30(188): 100-106 | Back to browse issues page

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Farzadi N, Salehifar E, Davoodi L, Abbaspour Kasgari H. Drug Utilization Evaluation of Imipenem and Assessing the Role of Pharmacist Interventions. J Mazandaran Univ Med Sci 2020; 30 (188) :100-106
URL: http://jmums.mazums.ac.ir/article-1-14871-en.html
Abstract:   (1389 Views)
Background and purpose: This study aimed at evaluating utilization of imipenem and assessing the role of pharmacist in rational use of antibiotics.
Materials and methods: A retrospective/prospective observational study was conducted in Ramsar Imam Sajjad Hospital in 59 patients receiving imipenem, 2018-2019. In retrospective phase, patients’ records were reviewed, while in prospective phase, a pharmacist provided recommendations on use of imipenem. Duration of taking imipenem, dosage, and dosage adjustment in renal insufficiency were compared with standard protocols.
Results: Mean age of the patients was 69.89±16.12 years and there were 29 males. The most common reason for prescribing imipenem was lower respiratory tract infection (54%) which was more used in internal medicine ward (67.28%) ordered by infectious diseases specialist (65%). In retrospective and prospective phases, mean dosage of imipenem, duration of receiving the antibiotic, and dosage adjustment in renal insufficiency were according to standard protocols in 65% and 85%,  45% and 65%, and 60% and 90% of the cases, respectively (P<0.001).
Conclusion: The role of pharmacist in drug utilization evaluations is of great importance for optimal use of drugs and reducing mortality rates caused by infectious diseases.
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Type of Study: Research(Original) | Subject: Clinical pharmacy

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