Volume 31, Issue 201 (10-2021)                   J Mazandaran Univ Med Sci 2021, 31(201): 28-38 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Dadgar K, Shadan L, Moazeni M, Biparva P, Yazdani Charati J, Ebrahimi Z et al . In vitro Analysis of Antifungal Effects of Acrylic Resin Modified by Zinc Oxide Nanoparticles on Candida albicans. J Mazandaran Univ Med Sci 2021; 31 (201) :28-38
URL: http://jmums.mazums.ac.ir/article-1-16891-en.html
Abstract:   (1127 Views)
Background and purpose: Removable prostheses made of polymethyl methacrylate are susceptible to Candida-dependent denture stomatitis and Candida albicans is considered to be the first common cause. The aim of the present study was to investigate the antifungal effect of acrylic resin modified by zinc oxide nanoparticles.
Materials and methods: In this laboratory study, 72 disks (10*4 mm) made of polymethyl methacrylate (Acropars, Marlic, Iran) were divided into three groups (n= 24). Concentrations of zinc oxide nanoparticles (ZnO NPs) were 1 (group A), 0.5 (group B), and 0 (group C, control) mg/ml. Samples were studied in laboratory using Candida albicans strains (ATCC 10231) according to CLSI M27-A3 and M27-S4 documents. For data analysis, one-way ANOVA and Scheffe's post-test were performed using SPSS V24.
Results: There were significant differences in mean numbers of fungal colonies in study groups. The amount of fungal colonies in group A was lower than those in group B and in group B was lower than those in group C (P<0.05).
Conclusion: Considering the limitations of this study, findings showed that zinc oxide nanoparticles have antifungal activity, which increases by increase in concentration of nanoparticles.
 
Full-Text [PDF 1317 kb]   (617 Downloads)    
Type of Study: Research(Original) | Subject: Dentistry

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb