Volume 33, Issue 224 ( 2023)                   J Mazandaran Univ Med Sci 2023, 33(224): 101-108 | Back to browse issues page

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Amini M, Mirzaei Ilali A, Mahmoudi F. Adverse Drug Reactions Reported in Healthcare Settings Affiliated to Mazandaran University of Medical Sciences, 2019-2021. J Mazandaran Univ Med Sci 2023; 33 (224) :101-108
URL: http://jmums.mazums.ac.ir/article-1-19202-en.html
Abstract:   (348 Views)
Background and purpose: Adverse drug reaction (ADR) is one of the main causes of mortality and morbidity and can contribute to high costs in healthcare system of a country. This study was conducted to evaluate ADRs in the Food and Drug deputy at Mazandaran University of Medical Sciences.
Materials and methods: This retrospective descriptive study was carried out after collecting the reports of yellow cards sent to the Center for Registration and Investigation of Adverse Drug Reaction in the Food and Drug Deputy of Mazandaran and the reports registered in the online system for registering medical complications and errors in 2019-2021. We analyzed data, including the frequency of the drugs with side effects, the frequency of routs of administration, number of reports per year, patient characteristics (gender and age), as well as the frequency of the organs damaged, and the reporters.
Results: A total of 2122 reports of adverse drug reactions were submitted to the Adverse Drug Reactions Center at Mazandaran Food and Drug Department. Nurses reported 52.78% of the side effects and 44.82% of the ADRs were seen in women. Injectable drugs were found with high rate of ADRs (87.40%) and the most prevalent side effects were associated with skin and hair disorders (28.07%). Anti-infective agents were the most common drugs that caused ADR (47.10%) and Vancomycin was found to be more prevalent than other drugs.
Conclusion: Adverse drug reactions were reported at a good level in Mazandaran province. It is believed that training the medical staff about pharmacovigilance and appropriate reporting, will bring us closer to world standards.
 
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Type of Study: Research(Original) | Subject: Pharmacy

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