Volume 19, Issue 71 (Jul 2009)                   J Mazandaran Univ Med Sci 2009, 19(71): 80-83 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Mahdavi M, Ghaemian A. Comparison of non-HDL cholestrol level with LDL, cholesterol and other lipids markers level regarding investigation of lipoproteins disorder in hospitalizedpatients in Mazandran Heart Hospital . J Mazandaran Univ Med Sci 2009; 19 (71) :80-83
URL: http://jmums.mazums.ac.ir/article-1-568-en.html
Abstract:   (13328 Views)
Background and purpose: Considering some restrictions of serum low density lipoprotein (LDL) as a marker for Coronary Artery Disease (CAD) risk factor and also the importance of apo B as a signinificant risk factor for CAD, measurement of non-HDL cholesterol has great value as a risk factor for CAD. Non-HDL cholesterol (total cholesterol minus HDL cholesterol) contains all lipoproteins including apo-lipoproteins.
Materials and methods: In this study, 200 hospitalized patients (100 men and 100 women) with the diagnosis of CAD, documented by coronary angiography and 100 persons with normal angiography were recruited as case and control groups, respectively. Non-HDL cholesterol non-HDL-c was compared with LDL- cholesterol as a risk factor for CAD.
Results: Measured levels of triglyceride, total cholesterol, lipoprotein atherogenic a (Lpa) and non-HDL-c were significantly higher than those in control group. HDL level was lower in patients group. Correlation analysis showed that non-HDL-c (and not LDL cholesterol) had a higher reverse correlation Triglyceride level.
Conclusion: Measurement of non-HDL-c could be a good marker in atherogenic lipoproteins. Furthermore, due to potential power of its other atherogenic lipoproteins, it cannot be measured by LDL alone.
Full-Text [PDF 194 kb]   (3079 Downloads)    
Type of Study: Research(Original) |

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Mazandaran University of Medical Sciences

Designed & Developed by : Yektaweb