Volume 27, Issue 158 (3-2018)                   J Mazandaran Univ Med Sci 2018, 27(158): 78-86 | Back to browse issues page

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Mardanshahi Z, Sakhaei Y, Khademloo M, Janbabi G, Aghili G, Tayebi M. Efficacy of Radiofrequency Ablation in Patients with Metastatic Liver Tumors from Breast Carcinoma . J Mazandaran Univ Med Sci. 2018; 27 (158) :78-86
URL: http://jmums.mazums.ac.ir/article-1-10133-en.html
Abstract:   (3709 Views)

Background and purpose: Breast cancer is the second leading cause of cancer death in women and the most common cancer causing liver metastases. Radiofrequency ablation (RFA) is a new method in treatment of liver metastases. This study was designed to evaluate the efficacy of RFA on liver metastatic breast tumors.
Materials and methods: In a randomized clinical trial, 52 patients with liver metastases from breast cancer who had less than 5 lesions < 5 cm enrolled. They were divided into two groups; an intervention group that received both chemotherapy and RFA and a control group who had only chemotherapy. Different variables were evaluated e.g. changes in lesion size, residual tumor status, and therapy complications. Data was analyzed in SPSS V20.  
Results: In a randomized clinical trial, 52 patients with liver metastases from breast cancer who had less than 5 lesions < 5 cm enrolled. They were divided into two groups; an intervention group that received both chemotherapy and RFA and a control group who had only chemotherapy. Different variables were evaluated e.g. changes in lesion size, residual tumor status, and therapy complications. Data was analyzed in SPSS V20.  
Conclusion: RFA was found as a safe and efficient method in treatment of liver metastases from breast carcinoma and showed a significant synergistic effect in patients under ingesting chemotherapy drugs.
 

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Type of Study: Research(Original) | Subject: Psychiatric Nursing

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