Volume 16, Issue 51 (Jul 2006)
J Mazandaran Univ Med Sci 2006, 16(51): 24-29 |
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Mirabi A, Rezaeipoor R, TabarMollaHassan A, Sharifnia Z, Ôkhravi H, Fadaie S, et al . The Effects of Electromagnetic Field on Cellular Immunity in BALB/c Mice. J Mazandaran Univ Med Sci 2006; 16 (51) :24-29
URL: http://jmums.mazums.ac.ir/article-1-107-en.html
URL: http://jmums.mazums.ac.ir/article-1-107-en.html
A.M Mirabi 
, R Rezaeipoor , A TabarMollaHassan , Z Sharifnia , H Ôkhravi , SH Fadaie , Y Mehrabi , A Âjami
, R Rezaeipoor , A TabarMollaHassan , Z Sharifnia , H Ôkhravi , SH Fadaie , Y Mehrabi , A Âjami
Abstract: (13968 Views)
Background and purpose: Ïn recent years, different studies have been performed regarding the influence of magnetic field on the immune system. There are many contraversies about the effects of different frequencies and amplitudes on the immune system.
Materials and methods : Ïn this experimental study, the effects of different frequencies of magnetic field (0,5,50,500 and 5000 Hz) have been determined on the innate & specific Ç.M.Ï. Â well known selected antigen such as SRBÇ was injected (108 /0.1ml) to different test and control groups (8 mice in each group). Ëach test group exposed to a defined frequency (0,5,50,500 and 5000Hz) of magnetic field with constant amplitude ( 0.4 mT) 8 hours daily for six consecative days. Çontrol groups were not exposed to any magnetic field while all other conditions were similar to the test groups. Ïnnate and specific cell mediated immunity were evaluated by NBT and DTH respectively.
Results : The NBT results showed that in all except zero frequencies of magnetic field, the level of respiratory burst were significantly reduced compared to the control group (P<0.001). The DTH responses were also decreased significantly in 500 Hz (P<0.034) and 5000 Hz (P<0.004) measured in 24 hours with no changes in zero, 5 and 50Hz frequencies, however in 48 and 72 hours no changes were measured in all frequencies .
Çonclusion: Ït can be concluded that frequencies of 5,50,500 and 5000 HZ reduce the innate immune response of BÂLBL/c mice but speceific cellular immunity remains unchanged.
Materials and methods : Ïn this experimental study, the effects of different frequencies of magnetic field (0,5,50,500 and 5000 Hz) have been determined on the innate & specific Ç.M.Ï. Â well known selected antigen such as SRBÇ was injected (108 /0.1ml) to different test and control groups (8 mice in each group). Ëach test group exposed to a defined frequency (0,5,50,500 and 5000Hz) of magnetic field with constant amplitude ( 0.4 mT) 8 hours daily for six consecative days. Çontrol groups were not exposed to any magnetic field while all other conditions were similar to the test groups. Ïnnate and specific cell mediated immunity were evaluated by NBT and DTH respectively.
Results : The NBT results showed that in all except zero frequencies of magnetic field, the level of respiratory burst were significantly reduced compared to the control group (P<0.001). The DTH responses were also decreased significantly in 500 Hz (P<0.034) and 5000 Hz (P<0.004) measured in 24 hours with no changes in zero, 5 and 50Hz frequencies, however in 48 and 72 hours no changes were measured in all frequencies .
Çonclusion: Ït can be concluded that frequencies of 5,50,500 and 5000 HZ reduce the innate immune response of BÂLBL/c mice but speceific cellular immunity remains unchanged.
Type of Study: Research(Original) |
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