Volume 30, Issue 185 (5-2020)                   J Mazandaran Univ Med Sci 2020, 30(185): 96-103 | Back to browse issues page

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Izadpanah F, Amini M, Asadollahpour A, Esfahani Z, Yousofi M. Adverse Drug Reactions in Mazandaran Province, Iran, 2004-2018. J Mazandaran Univ Med Sci. 2020; 30 (185) :96-103
URL: http://jmums.mazums.ac.ir/article-1-14541-en.html
Abstract:   (561 Views)
Background and purpose: Adverse drug reaction (ADR) is one of the major causes of mortality and morbidity in patients that results in high healthcare costs. This study was conducted in Food and Drug Deputy at Mazandaran University to evaluate ADRs in Mazandaran province.
Materials and methods: The analysis was performed during 2004-2018, based on the frequency of the drugs that had side effects, routes of administration, the number of reports per year, patient characteristics (gender, age), the frequency of the organ damaged, and the reporter.
Results: A total of 4425 reports of ADRs were submitted to Adverse Drug Reactions Center in Food and Drug Department, Mazandaran province, Iran. More than half of the reports (61%) were reported by nurses and 58.4% of the ADRs occurred in women. Injectable drugs were found with more adverse effects (75.7%) and the most prevalent were skin and hair disorders (50.6%). Anti-infective agents were the top drugs that caused ADRs (52.2%) and ceftriaxone was the most prevalent.
Conclusion: Due to the low number of ADRs in Mazandaran province and its low concordance with international standards, it seems that trainings based on the needs and preferences of medical groups about pharmacovigilance and focuses on how to report, can increase their awareness and knowledge about ADR and bring the data closer to world standards.
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Type of Study: Research(Original) | Subject: Clinical pharmacy

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