Volume 31, Issue 198 (7-2021)
J Mazandaran Univ Med Sci 2021, 31(198): 48-59 |
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Nejati B, Sayedi S J, Shokohi T, Hedayati M T, Nabili M, Mousavi S J, et al . Pediatric Catheters Infectivity and Identification of Candida Species Isolated from Hospitalized Patients in Mashhad Pediatric Hospital. J Mazandaran Univ Med Sci 2021; 31 (198) :48-59
URL: http://jmums.mazums.ac.ir/article-1-15521-en.html
URL: http://jmums.mazums.ac.ir/article-1-15521-en.html
Bahar Nejati 
, Seyed Javad Sayedi , Tahereh Shokohi , Mohammad Taghi Hedayati , Mojtaba Nabili , Seyed Jaber Mousavi , Mohamad Esmaeeli , Maryam Moazeni
, Seyed Javad Sayedi , Tahereh Shokohi , Mohammad Taghi Hedayati , Mojtaba Nabili , Seyed Jaber Mousavi , Mohamad Esmaeeli , Maryam Moazeni
Abstract: (1531 Views)
Background and purpose: Invasive candidiasis in infants has high mortality rate and is often associated with colonization on medical devices such as catheters. Candida colonization is considered as a predisposing factor for Candida related infection. The aim of this study was to evaluate the rate of catheters infectivity by Candida species.
Materials and methods: In this descriptive cross-sectional study, sampling was done from catheters of hospitalized children (0-18 years old) in pediatric intensive care unit (PICU) in Mashhad Dr. Sheikh Hospital, June-November 2018. All catheters were evaluated to determine the extent of contamination and early identification of isolates was done by morphological and molecular methods.
Results: The types of catheter infectivity for 114 samples included colonization or infective (n=25 isolates, 21.92%), contamination (n=4, 3.5%), and no growth (n=85 isolates, 56.74%). The most isolated species was C. albicans (n=18, 13.39%), followed by C. glabrata (n=9, 19.56%), C. krusei and C. parapsilosis (n=7, 15.21%, each isolate), C. tropicalis (n=3, 6.25%), and C. lusitaniae and C. kefyr (n=1, 2.17% each isolate).
Conclusion: Isolation of Candida species in 25% of catheters raised the possibility of colonization, considering the catheters as an exogenous potential source of candidiasis which is very important in PICU.
Materials and methods: In this descriptive cross-sectional study, sampling was done from catheters of hospitalized children (0-18 years old) in pediatric intensive care unit (PICU) in Mashhad Dr. Sheikh Hospital, June-November 2018. All catheters were evaluated to determine the extent of contamination and early identification of isolates was done by morphological and molecular methods.
Results: The types of catheter infectivity for 114 samples included colonization or infective (n=25 isolates, 21.92%), contamination (n=4, 3.5%), and no growth (n=85 isolates, 56.74%). The most isolated species was C. albicans (n=18, 13.39%), followed by C. glabrata (n=9, 19.56%), C. krusei and C. parapsilosis (n=7, 15.21%, each isolate), C. tropicalis (n=3, 6.25%), and C. lusitaniae and C. kefyr (n=1, 2.17% each isolate).
Conclusion: Isolation of Candida species in 25% of catheters raised the possibility of colonization, considering the catheters as an exogenous potential source of candidiasis which is very important in PICU.
Type of Study: Research(Original) |
Subject:
mycology
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