Volume 34, Issue 241 (1-2025)
J Mazandaran Univ Med Sci 2025, 34(241): 29-41 |
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Dehghan Naeiri E, Nasiri Formi E, Pezeshkpoor Z, Khodabakhsh E. Comparison of the Effect of Using Tranexamic Acid and Position on Cesarean Section Bleeding Rate, Surgical Team Satisfaction and Postoperative Complications, A Randomized Control Trial. J Mazandaran Univ Med Sci 2025; 34 (241) :29-41
URL: http://jmums.mazums.ac.ir/article-1-21135-en.html
URL: http://jmums.mazums.ac.ir/article-1-21135-en.html
Abstract: (518 Views)
Background and purpose: Bleeding is a serious complication of cesarean sections that can lead to decreased hemoglobin levels and increased maternal and neonatal mortality. This study aimed to compare the effects of tranexamic acid and position changes on the amount of bleeding and the satisfaction of the surgical team.
Materials and methods: This study is a randomized, controlled, parallel clinical trial. The amount of bleeding, hemodynamic parameters, demographic data, clinical parameters, and surgical team satisfaction were measured using validated instruments. The study population consisted of patients aged 18 to 40 years who were candidates for cesarean sections under general anesthesia at Shohada Kargar Hospital in Yazd. The samples were randomly assigned to three groups each containing 33 participants: tranexamic acid, position change, and control. Data were analyzed using SPSS V.22 software.
Results: A total of 99 pregnant women with a mean age of 31.20±5.82 years were included in the study. No significant differences were found in changes in hemoglobin, hematocrit, platelets, blood pressure, or oxygen saturation between the groups (P>0.05). The mean total bleeding in the tranexamic acid and position change groups was significantly lower than that in the control group (P<0.05). Additionally, satisfaction rates in the tranexamic acid and position change groups were higher than in the control group (P<0.001), but no significant difference was observed between the tranexamic acid and position change groups (P=0.472).
Conclusion: The results indicated that tranexamic acid and position changes significantly reduced bleeding and increased surgical team satisfaction, without negatively affecting postoperative complications. Therefore, the use of tranexamic acid and position changes can be recommended as effective strategies for reducing bleeding and enhancing surgical team satisfaction during cesarean section procedures.
(Clinical Trials Registry Number: IRCT20240421061546N1)
Materials and methods: This study is a randomized, controlled, parallel clinical trial. The amount of bleeding, hemodynamic parameters, demographic data, clinical parameters, and surgical team satisfaction were measured using validated instruments. The study population consisted of patients aged 18 to 40 years who were candidates for cesarean sections under general anesthesia at Shohada Kargar Hospital in Yazd. The samples were randomly assigned to three groups each containing 33 participants: tranexamic acid, position change, and control. Data were analyzed using SPSS V.22 software.
Results: A total of 99 pregnant women with a mean age of 31.20±5.82 years were included in the study. No significant differences were found in changes in hemoglobin, hematocrit, platelets, blood pressure, or oxygen saturation between the groups (P>0.05). The mean total bleeding in the tranexamic acid and position change groups was significantly lower than that in the control group (P<0.05). Additionally, satisfaction rates in the tranexamic acid and position change groups were higher than in the control group (P<0.001), but no significant difference was observed between the tranexamic acid and position change groups (P=0.472).
Conclusion: The results indicated that tranexamic acid and position changes significantly reduced bleeding and increased surgical team satisfaction, without negatively affecting postoperative complications. Therefore, the use of tranexamic acid and position changes can be recommended as effective strategies for reducing bleeding and enhancing surgical team satisfaction during cesarean section procedures.
(Clinical Trials Registry Number: IRCT20240421061546N1)
Type of Study: Research(Original) |
Subject:
anesthesia
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