Volume 35, Issue 248 (9-2025)
J Mazandaran Univ Med Sci 2025, 35(248): 150-158 |
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Salimi M, Moslemi A, Montazeri M, Shokohi T. Prevention and Control of Nosocomial Candida Infections Caused by Antifungal-Resistant Species in Iran: A Policy Brief. J Mazandaran Univ Med Sci 2025; 35 (248) :150-158
URL: http://jmums.mazums.ac.ir/article-1-21625-en.html
URL: http://jmums.mazums.ac.ir/article-1-21625-en.html
Abstract: (19 Views)
Hospital-acquired infections caused by drug-resistant Candida species represent a serious threat to patient health, particularly among individuals in intensive care units and patients with immune deficiencies or chronic diseases. In recent years, the increasing incidence of these infections has posed a growing challenge to Iran’s healthcare system. The Invasive Fungi Research Center, affiliated with Mazandaran University of Medical Sciences, presents this policy brief using an evidence-based, clinically oriented approach, considering the practical realities of Iranian hospitals. It proposes a set of practical strategies for the prevention, diagnosis, and effective management of hospital-acquired infections caused by drug-resistant Candida species.
These strategies are designed around three key components: reducing the survival of Candida species, preventing transmission of infection, and minimizing drug resistance. Implementation is recommended in phases, accompanied by structural reinforcement and policy support, taking into account existing capacities and resources.
Three urgent and critical priorities include: strengthening infection prevention and control systems in hospitals, rapid implementation of guidelines for the rational use of antifungal drugs, and enhancing laboratory diagnostic capacity for early detection of drug-resistant Candida species.
Among the most important mid-term measures are: developing and implementing a national program for managing antifungal drug consumption, and establishing an integrated system to monitor fungal drug resistance.
Key long-term measures include: investing in research and development of new antifungal agents, establishing an electronic referral system to control the spread of resistant species at the national level, and training specialized personnel in medical mycology
These strategies are designed around three key components: reducing the survival of Candida species, preventing transmission of infection, and minimizing drug resistance. Implementation is recommended in phases, accompanied by structural reinforcement and policy support, taking into account existing capacities and resources.
Three urgent and critical priorities include: strengthening infection prevention and control systems in hospitals, rapid implementation of guidelines for the rational use of antifungal drugs, and enhancing laboratory diagnostic capacity for early detection of drug-resistant Candida species.
Among the most important mid-term measures are: developing and implementing a national program for managing antifungal drug consumption, and establishing an integrated system to monitor fungal drug resistance.
Key long-term measures include: investing in research and development of new antifungal agents, establishing an electronic referral system to control the spread of resistant species at the national level, and training specialized personnel in medical mycology
Keywords: Nosocomial infection, invasive candida infection, candidemia, antifungal resistance, infection control, prevention, policy brief f
Subject:
Epidemiology
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