Volume 17, Issue 61 (Sep 2007)                   J Mazandaran Univ Med Sci 2007, 17(61): 141-147 | Back to browse issues page

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Ghasemi M, Alam A, Karami H, Salimi S. Case Series of 111 Hirschsprung`s disease among chronic constipated children referring to BooAli Sina Hospital from 1997 to 2006. J Mazandaran Univ Med Sci 2007; 17 (61) :141-147
URL: http://jmums.mazums.ac.ir/article-1-275-en.html
Abstract:   (19881 Views)
Background and Purpose: Hirschsprung`s disease (HD) as an organic cause of children constipation is only treated by surgical intervention. Regarding of variety of clinical manifestation of HD and lack of information about it in Sari, this study describes the prevalence of HD in constipated children referring to BooAli Hospital.
Materials and Methods: this descriptive study was undertaken on children with protracted constipation and neonate suspicions for HD referring to BooAli Sina Hospital of Sari (1997-2006). Clinical and pathological data of patients were collected from their records and analyzed using SPSS 13 software.
Results: 226 children were presented with constipation at a mean age of 30.6±34.8 months (range, 0.69-1.6 months). Rectal biopsy performed in 187 cases. HD was diagnosed in 59.4% of biopsied patients. The mean age of patients diagnosed was 24.8± 33.2 months. 27.1% patients with HD were diagnosed in the first month, 44.1% in 1-12, 18% in 12-48 and 10.8% in over 48 months.
Conclusion: This study revealed 59.4% of protected chronically constipated children had HD, indicating usefulness of rectal biopsy in these patients.
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