Volume 23, Issue 109 (1-2014)
J Mazandaran Univ Med Sci 2014, 23(109): 2-7 |
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Golshani S, Bagheri B, Ghaemian A, Mokhberi V, Azizi S, Khaninian A et al . Association of serum N-Terminal pro BNP in the Prediction Association of Serum N-Terminal pro BNP in Prediction of Left Ventricular Ejection Fraction in Patients with Systolic Ventricular Dysfunction. J Mazandaran Univ Med Sci 2014; 23 (109) :2-7
URL: http://jmums.mazums.ac.ir/article-1-3293-en.html
URL: http://jmums.mazums.ac.ir/article-1-3293-en.html
Samad Golshani 
, Babak Bagheri , Ali Ghaemian , Vahid Mokhberi , Soheil Azizi , Alireza Khaninian , Mehdi Nemati
, Babak Bagheri , Ali Ghaemian , Vahid Mokhberi , Soheil Azizi , Alireza Khaninian , Mehdi Nemati
Abstract: (12139 Views)
Background and purpose: Annually heart failure includes about three million emergency outpatient visits in the United States. In heart failure NT-proBNP will be released in response to increased myocardial stretch
Materials and methods: This study was conducted in 80 individuals attending Fatemeh Zahra Hospital, in Sari, 2010-2011. Patients with GFR≤60, age≥75, atrial fibrillation (AF) and hypertension (BP≥160.100) were excluded. The patients were carefully examined and 60 patients with DHF were divided into three groups Group1 LVEF≤30%, group 2 LVEF≤31-39%, group 3 LVEF≤40-49%. Twenty healthy people with normal LVEF≥50% were also studied to determine the cut point.
Results: The highest level of NT-pro BNP was observed in group 1 (5370.10 ± 1781.90) and the lowest level was seen in group 4 (36.75 ± 24.32). Significant differences were found between the groups in NT-pro BNP level (P<0.001). Also, incomplete and reverse correlation was observed between LVEF values and serum level NT-pro BNP (R= -0.699).
Conclusion: When LVEF reduced NT-pro BNP levels increased significantly which indicates an incomplete and reverse correlation between them. This finding allows using NT-pro BNP level for approximate estimation of ejection fraction in clinical practices.
Type of Study: Research(Original) |
Subject:
Microbiology
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