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Background and purpose: Imaging which is used in nuclear medicine is done using emit gamma rays whereas therapy in nuclear medicine is performed by applying radionuclide’s which emit beta radiation. Using Bremsstrahlung is a new field which is recently introduced in imaging. In the Bremsstrahlung imaging, collimator design should not be based on energy peak and whole energy spectrum should be considered. The main problem of these radiations is collimator penetration. This study suggests a new design for collimator in Bremsstrahlung imaging which weighs less than half of usual collimators. This design will somewhat influence the resolution and sensitivity. Furthermore, the effect of wiener filter in Bremsstrahlung imaging is also considered Material and Methods: Layer collimator in forms of digital phantom was designed by GATE simulator and its sensitivity and resolution in deferent layers was evaluated. Results: By increasing collimator layers, sensitivity rose by 9%, in contrast, due to penetration resolution decreased to 11%. Furthermore, we did not find any evidence that showed wiener filter in Bremsstrahlung imaging improved resolution. Conclusion: In this study, layer collimator has increased the sensitivity, consequently, the time required for collecting count for Bremsstrahlung imaging has decreased.

Keywords: Nuclear medicine, Monte Carlo, Collimator, Bremsstrahlung, Phosphorus 32

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