Volume 25, Issue 129 (10-2015)                   J Mazandaran Univ Med Sci 2015, 25(129): 128-131 | Back to browse issues page

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Saeedi M, Hajheydari Z, Akbari J, MortezaSemnani K, Emadian A. Preparation of Malathion 0.5% Lotion and Studying its Effect on Healing Scabies Compared With Permethrin Cream 5%. J Mazandaran Univ Med Sci. 2015; 25 (129) :128-131
URL: http://jmums.mazums.ac.ir/article-1-6257-en.html
Abstract:   (7944 Views)
Background and purpose: Scabies is caused by a mite called Sarcoptes scabiei and can be spread from person to person through skin contact. In this study, we have analyzed the effect of Malathion lotion 0.5% and compared that with the effect of Permethrin cream 0.5%. Materials and methods: In a randomized clinical trial 60 patients were divided into two groups to receive either Permethrin cream 5% or Malathion lotion 0.5%. Both groups were monitored every two weeks for one month. The qualitative data of both groups were compared using student t-test and chi-square test was applied to analyze the qualitative data. Results: There was no significant difference between the two groups in number of lesions at the begging of the study (P=0.1503). Also, no significant difference was seen in weeks two and four. But Malathion lotion was found to be more efficient than Permethrin (P=0.0163) in reducing the number of lesions although the results were better in week four, but the difference was not significant (P=0.2940). Conclusion: This study showed high efficacy of Malathion 5% in treating scabies.
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Type of Study: Brief Report | Subject: Pharmacy

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