Volume 21, Issue 84 (Sep 2011)                   J Mazandaran Univ Med Sci 2011, 21(84): 113-120 | Back to browse issues page

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Abyar H, GHafari V, Nakhshab M, Jafari M, Rahimi N, Asadpour S. Nasal Intermittent Mandatory Ventilation (NIMV) Versus Nasal Continuous Positive Airway Pressure (NCPAP) in Weaning from Mechanical Ventilation in Preterm Infants. J Mazandaran Univ Med Sci 2011; 21 (84) :113-120
URL: http://jmums.mazums.ac.ir/article-1-676-en.html
Abstract:   (13431 Views)
Background and purpose: Respiratory disorders and need for mechanical ventilation are common complications in preterm infants. Âttention has been drawn to premature weaning from ventilator and also removal of endotracheal tube with an approach towards reduction of risks. This study has been carried out to compare the outcomes of two methods of NÏMV and NÇPÂP in infants afflicted with respiratory distress syndrome under mechanical ventilation.
Materials and methods: This study is a randomized clinical study that has been conducted throughout 2009 to 2010. Â total of 40 infants in two groups of case and control have been studied. Ïnfants of 28 to 32 and 32 to 37 weeks of age were randomly placed in two NÏMV and NÇPÂP groups and re-intubation, and complications of the two methods were compared in infants.
Results: Ïnfants in the two groups were identical regarding gender, gestational age, birth weight, type of delivery, mechanical ventilation period and use of surfactant and steroids prior to delivery. Re-intubation, respiratory acidosis and intra-ventricular hemorrhage were less in NÏMV group (p<0.05). There was no significant difference in apnea, hypoxia, pneumothorax, feeding intolerance, abdominal distention, length of hospitalization and death rates.
Çonclusion: The study has shown that respiratory acidosis in NÏMV group is less in comparison to NÇPÂP group. Therefore, in order to prevent re-intubation and occurrence of respiratory acidosis and to reduce occurrence of intra-ventricular hemorrhage in infants suffering from respiratory distress syndrome in time of weaning from mechanical ventilation, it is necessary to use the NÏMV method.
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Type of Study: Research(Original) |

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