Periodontal disease is one of the most common chronic infectious diseases in humans. In recent years, an association was found between periodontitis and some systemic diseases such as cardiovascular disorders, problems during pregnancy, diabetes, cerebrovascular diseases, and respiratory disorders. Complications that may arise during pregnancy include pretem birth, low birth weight, intrauterine growth restriction, and preeclampsia. The association between periodontitis and preeclampia is discussed in this article by reviewing relevant data.